Cheng Jian, Xie Jin, Zhu Chengjian
State Key Laboratory of Coordination Chemistry, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing, 210023, P. R. China.
Chem Commun (Camb). 2018 Feb 14;54(13):1655-1658. doi: 10.1039/c7cc09820k. Epub 2018 Jan 29.
A relay photoredox catalysis strategy concomitant with [1,5] hydrogen atom transfer has been applied in the construction of a biologically important indolo[2,1-a]isoquinoline framework via a cascade reaction. This reaction enables double C(sp)-H bond functionalization and formation of two carbon-carbon double bonds from readily available starting materials in an efficient and step-economical manner.
一种与[1,5]氢原子转移相伴的接力光氧化还原催化策略已被应用于通过串联反应构建具有生物学重要性的吲哚并[2,1-a]异喹啉骨架。该反应能够以高效且步骤经济的方式实现双C(sp)-H键官能化，并从易得的起始原料形成两个碳-碳双键。
