Jie Zhou, Wei Guan, Fu-Rong Wei, Yao Ruan, Sheng-Ming Li, Jing Xu, Tie-Wu Jia, Xiao-Nong Zhou
Hunan Provincial Institute of Schistosomiasis Control, Yueyang 414000, China.
National Institute of Parasite Diseases, Chinese Center for Disease Control and Prevention.
Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2016 May 31;28(4):375-380. doi: 10.16250/j.32.1374.2015252.
To evaluate the value of indirect hemagglutination test (IHA) in schistosomiasis diagnosis.
The literature concerned schistosomiasis diagnosis with IHA in the databases of Medline, CNKI, VIP and Wanfang Data from 1982 to 2014 was collected and evaluated.
Totally 21 articles which were satisfied with the research criteria were analyzed with the Meta-analysis method. The IHA method had high value in schistosomiasis diagnosis, the AUC of IHA in laboratory evaluation was 0.990 6, while in filed evaluation was 0.832 9, and the difference between them was significant ( = 4.50, < 0.05).
The diagnosis value of IHA in field evaluation is less than that in laboratory. In the process of the elimination of schistosomiasis, developing a new and higher sensitive reagent in schistosomiasis diagnosis is needed.
