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双管法治疗自发性食管破裂并纵隔感染

Two-tube method for treatment of spontaneous esophageal rupture and concomitant mediastinal infection.

作者信息

Yu Liang-Liang, He Zheng-Fu, Liu Qi-Fang, Dai Ning, Si Jian-Min, Ye Bei, Zhou Jian-Cang

机构信息

1 Department of Gastroenterology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

2 Department of Thoracic Surgery, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, China.

出版信息

J Int Med Res. 2018 Apr;46(4):1528-1536. doi: 10.1177/0300060517752995. Epub 2018 Jan 29.

Abstract

Objective Spontaneous esophageal rupture (SER) is a rare but life-threatening condition with high mortality. The prognosis of patients with SER treated with surgical intervention or the traditional "three-tube" method is controversial. Thus, the aim of this study was to evaluate the clinical efficacy, feasibility, and safety of a new "two-tube" method involving a trans-fistula drainage tube and a three-lumen jejunal feeding tube for the treatment of SER without concomitant pleural rupture. Methods From January 2007 to June 2016, patients with SER and managed with the "two-tube" method or other methods were retrospectively analyzed. Data collected included initial presentation, procedure time, duration of treatment, numbers of patients with eventual healing of leaks, and complications. Results The average procedure time for the "two-tube" method was 22.1 ± 5.5 minutes. In comparison with the control method, the "two-tube" method had a similar diagnosis time (3.6 ± 1.4 vs. 3.4 ± 1.4 days) but a significantly higher successful closure rate (94.4% vs. 63.6%) and shorter treatment time (38.2 ± 5.6 vs. 53.6 ± 16.9 days). No complications associated with performance of the "two-tube" method occurred. Conclusion The "two-tube" method is an effective and safe approach for patients with SER.

摘要

目的 自发性食管破裂(SER)是一种罕见但危及生命的疾病,死亡率很高。采用手术干预或传统“三管”法治疗的SER患者的预后存在争议。因此,本研究的目的是评估一种新的“双管”法(包括经瘘引流管和三腔空肠喂养管)治疗无合并胸膜破裂的SER的临床疗效、可行性和安全性。方法 回顾性分析2007年1月至2016年6月采用“双管”法或其他方法治疗的SER患者。收集的数据包括初始表现、手术时间、治疗持续时间、最终漏口愈合的患者数量和并发症。结果 “双管”法的平均手术时间为22.1±5.5分钟。与对照方法相比,“双管”法的诊断时间相似(3.6±1.4天对3.4±1.4天),但成功闭合率显著更高(94.4%对63.6%),治疗时间更短(38.2±5.6天对53.6±16.9天)。未发生与“双管”法操作相关的并发症。结论 “双管”法是治疗SER患者的一种有效且安全的方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4349/6091846/c221ad476331/10.1177_0300060517752995-fig1.jpg

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