Department of Interventional Radiology, The First Affiliated Hospital of Zhengzhou University, No. 1, East Jian She Road, Zhengzhou, 450052, China.
Department of Histology and Embryology, College of Basic Medicine, Zhengzhou University, Zhengzhou, China.
Radiol Med. 2019 Dec;124(12):1253-1261. doi: 10.1007/s11547-019-01074-0. Epub 2019 Aug 19.
We aimed to determine the safety, feasibility and efficacy of interventional radiology method for the management of esophagogastric anastomotic leakage.
We retrospectively assessed the medical records of 23 consecutive patients with esophagogastric anastomotic leakage treated using intervention protocol. Patients received three-tube method (abscess drainage tube, gastrointestinal decompression tube and jejunal feeding tube) with or without temporary covered esophageal stent placement. Abscess drainage, anti-inflammatory treatment and nutritional support were performed thereafter. The esophageal stents and three tubes were removed after leakage healing.
All patient received three-tube method and eight patients received covered stent placement. All operations were technically successful. After a median of 2.4 months, the stents were successfully removed from five patients. No death, esophageal rupture or massive hemorrhage occurred during procedures. The abscess cavity had markedly decreased in seven patients or disappeared in 16 cases. During follow-up, four patients died of cancer recurrence, one died of heart dysfunction and one died of pulmonary infection. The 1-, 3-, 5-year survival rates were 86.4%, 52.3% and 52.3%, respectively.
Interventional radiology protocol is safe, feasible and efficacious for treatment for esophagogastric anastomotic leakage.
本研究旨在确定介入放射学方法在治疗食管胃吻合口瘘中的安全性、可行性和疗效。
我们回顾性评估了 23 例采用介入治疗方案治疗的食管胃吻合口瘘患者的病历。患者接受三管法(脓肿引流管、胃肠减压管和空肠喂养管)治疗,或在必要时临时放置覆盖性食管支架。此后进行脓肿引流、抗炎治疗和营养支持。在漏口愈合后,取出食管支架和三根管子。
所有患者均接受了三管法治疗,8 例患者接受了覆盖性支架置入。所有手术均技术成功。中位随访 2.4 个月后,5 例患者成功取出支架。在操作过程中,无死亡、食管破裂或大出血发生。7 例患者脓肿腔明显缩小,16 例患者脓肿腔消失。随访期间,4 例患者死于癌症复发,1 例死于心功能不全,1 例死于肺部感染。1、3、5 年生存率分别为 86.4%、52.3%和 52.3%。
介入放射学方案治疗食管胃吻合口瘘是安全、可行和有效的。