• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.

作者信息

Lampe Sebastian, Kunze Michael, Scholz Anica, Brauß Thilo F, Winslow Sofia, Simm Stefan, Keller Mario, Heidler Juliana, Wittig Ilka, Brüne Bernhard, Schmid Tobias

机构信息

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.

Department of Molecular Cell Biology of Plants, Faculty of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.

出版信息

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31.

DOI:10.1016/j.bbagrm.2018.01.010
PMID:29378331
Abstract
摘要

相似文献

1
Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.TXNIP内部核糖体进入位点的鉴定及调控性内部核糖体进入位点反式作用因子影响的表征。
Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31.
2
Polypyrimidine Tract-Binding Protein Regulates Enterovirus 71 Translation Through Interaction with the Internal Ribosomal Entry Site.多嘧啶 tract 结合蛋白通过与内部核糖体进入位点的相互作用调节肠道病毒 71 的翻译。
Virol Sin. 2019 Feb;34(1):66-77. doi: 10.1007/s12250-019-00089-1. Epub 2019 Feb 22.
3
La Autoantigen Induces Ribosome Binding Protein 1 (RRBP1) Expression through Internal Ribosome Entry Site (IRES)-Mediated Translation during Cellular Stress Condition.自身抗原在细胞应激条件下通过内部核糖体进入位点（IRES）介导的翻译诱导核糖体结合蛋白1（RRBP1）表达。
Int J Mol Sci. 2016 Jul 20;17(7):1174. doi: 10.3390/ijms17071174.
4
The up regulation of phosphofructokinase1 (PFK1) protein during chemically induced hypoxia is mediated by the hypoxia-responsive internal ribosome entry site (IRES) element, present in its 5'untranslated region.化学诱导的缺氧过程中磷酸果糖激酶1（PFK1）蛋白的上调是由其5'非翻译区存在的缺氧反应性内部核糖体进入位点（IRES）元件介导的。
Biochimie. 2017 Aug;139:38-45. doi: 10.1016/j.biochi.2017.05.012. Epub 2017 May 22.
5
Polypyrimidine tract-binding protein binds to the 5' untranslated region of the mouse mammary tumor virus mRNA and stimulates cap-independent translation initiation.聚嘧啶序列结合蛋白与小鼠乳腺肿瘤病毒mRNA的5'非翻译区结合，并刺激不依赖帽结构的翻译起始。
FEBS J. 2016 May;283(10):1880-901. doi: 10.1111/febs.13708. Epub 2016 Apr 5.
6
The 5'-untranslated region of p16INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding.p16INK4a黑色素瘤肿瘤抑制因子的5'-非翻译区作为一种细胞内部核糖体进入位点，通过与YBX1结合在缺氧条件下控制mRNA翻译。
Oncotarget. 2015 Nov 24;6(37):39980-94. doi: 10.18632/oncotarget.5387.
7
Polypyrimidine tract binding protein and poly r(C) binding protein 1 interact with the BAG-1 IRES and stimulate its activity in vitro and in vivo.聚嘧啶序列结合蛋白和聚胞嘧啶结合蛋白1与BAG-1内部核糖体进入位点相互作用，并在体外和体内刺激其活性。
Nucleic Acids Res. 2003 Jan 15;31(2):639-46. doi: 10.1093/nar/gkg146.
8
Polypyrimidine tract-binding protein inhibits translation of bip mRNA.多聚嘧啶序列结合蛋白抑制bip mRNA的翻译。
J Mol Biol. 2000 Nov 24;304(2):119-33. doi: 10.1006/jmbi.2000.4179.
9
Identification of the internal ribosome entry sites in the 5'‑untranslated region of the gene.鉴定基因 5' 非翻译区内部核糖体进入位点。
Int J Mol Med. 2021 Apr;47(4). doi: 10.3892/ijmm.2021.4889. Epub 2021 Feb 19.
10
unr, a cellular cytoplasmic RNA-binding protein with five cold-shock domains, is required for internal initiation of translation of human rhinovirus RNA.Unr是一种具有五个冷休克结构域的细胞胞质RNA结合蛋白，是人类鼻病毒RNA翻译的内部起始所必需的。
Genes Dev. 1999 Feb 15;13(4):437-48. doi: 10.1101/gad.13.4.437.

引用本文的文献

1
Understanding the Role of the SMN Complex Component GEMIN5 and Its Functional Relationship with Demethylase KDM6B in the Flunarizine-Mediated Neuroprotection of Motor Neuron Disease Spinal Muscular Atrophy.理解 SMN 复合物成分 GEMIN5 的作用及其与去甲基酶 KDM6B 在氟桂利嗪介导的运动神经元疾病脊髓性肌萎缩神经保护中的功能关系。
Int J Mol Sci. 2024 Sep 18;25(18):10039. doi: 10.3390/ijms251810039.
2
Long non-coding RNA and paraspeckle components are translational regulators in hypoxia.长非编码 RNA 和核周斑点成分是低氧环境中的翻译调节因子。
Elife. 2022 Dec 22;11:e69162. doi: 10.7554/eLife.69162.
3
G-Quadruplex Regulation of mRNA Translation by RBM4.
RBM4 通过 G-四链体调控 mRNA 翻译。
Int J Mol Sci. 2022 Jan 11;23(2):743. doi: 10.3390/ijms23020743.
4
Identification of Gm15441, a Txnip antisense lncRNA, as a critical regulator in liver metabolic homeostasis.鉴定Gm15441，一种Txnip反义长链非编码RNA，作为肝脏代谢稳态的关键调节因子。
Cell Biosci. 2021 Dec 14;11(1):208. doi: 10.1186/s13578-021-00722-1.
5
Protein synthesis inhibitors stimulate MondoA transcriptional activity by driving an accumulation of glucose 6-phosphate.蛋白质合成抑制剂通过促使6-磷酸葡萄糖积累来刺激MondoA转录活性。
Cancer Metab. 2020 Dec 4;8(1):27. doi: 10.1186/s40170-020-00233-6.
6
Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting.长链非编码 RNA Gm15441 可减弱过氧化物酶体增殖物激活受体激动剂和禁食诱导的肝炎症小体激活。
Nat Commun. 2020 Nov 17;11(1):5847. doi: 10.1038/s41467-020-19554-7.
7
Emerging Roles of Gemin5: From snRNPs Assembly to Translation Control.Gemini5 的新兴作用：从 snRNPs 组装到翻译控制。
Int J Mol Sci. 2020 May 29;21(11):3868. doi: 10.3390/ijms21113868.
8
The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases.小分子氟桂利嗪对脊髓性肌萎缩症患者成纤维细胞中运动神经元疾病相关RNA结合蛋白TDP43及SMN复合物的双子组件产生影响。
Front Mol Biosci. 2020 Apr 17;7:55. doi: 10.3389/fmolb.2020.00055. eCollection 2020.
9
IRES Trans-Acting Factors, Key Actors of the Stress Response.IRES 转译因子：应激反应的关键因素。
Int J Mol Sci. 2019 Feb 20;20(4):924. doi: 10.3390/ijms20040924.
10
Deconstructing internal ribosome entry site elements: an update of structural motifs and functional divergences.解构内部核糖体进入位点元件：结构模体和功能分歧的更新。
Open Biol. 2018 Nov 28;8(11):180155. doi: 10.1098/rsob.180155.