TXNIP内部核糖体进入位点的鉴定及调控性内部核糖体进入位点反式作用因子影响的表征。 - Suppr

Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.

作者信息

Lampe Sebastian, Kunze Michael, Scholz Anica, Brauß Thilo F, Winslow Sofia, Simm Stefan, Keller Mario, Heidler Juliana, Wittig Ilka, Brüne Bernhard, Schmid Tobias

机构信息

Institute of Biochemistry I, Faculty of Medicine, Goethe-University Frankfurt, 60590 Frankfurt, Germany.

Department of Molecular Cell Biology of Plants, Faculty of Biosciences, Goethe-University Frankfurt, 60438 Frankfurt, Germany.

出版信息

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31.

DOI:10.1016/j.bbagrm.2018.01.010

PMID:29378331

Abstract

摘要

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Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.TXNIP内部核糖体进入位点的鉴定及调控性内部核糖体进入位点反式作用因子影响的表征。

Biochim Biophys Acta Gene Regul Mech. 2018 Feb;1861(2):147-157. doi: 10.1016/j.bbagrm.2018.01.010. Epub 2018 Jan 31.

Polypyrimidine Tract-Binding Protein Regulates Enterovirus 71 Translation Through Interaction with the Internal Ribosomal Entry Site.多嘧啶 tract 结合蛋白通过与内部核糖体进入位点的相互作用调节肠道病毒 71 的翻译。

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La Autoantigen Induces Ribosome Binding Protein 1 (RRBP1) Expression through Internal Ribosome Entry Site (IRES)-Mediated Translation during Cellular Stress Condition.自身抗原在细胞应激条件下通过内部核糖体进入位点（IRES）介导的翻译诱导核糖体结合蛋白1（RRBP1）表达。

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The up regulation of phosphofructokinase1 (PFK1) protein during chemically induced hypoxia is mediated by the hypoxia-responsive internal ribosome entry site (IRES) element, present in its 5'untranslated region.化学诱导的缺氧过程中磷酸果糖激酶1（PFK1）蛋白的上调是由其5'非翻译区存在的缺氧反应性内部核糖体进入位点（IRES）元件介导的。

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Identification of the TXNIP IRES and characterization of the impact of regulatory IRES trans-acting factors.

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