Asutay F, Yolcu Ü, Geçör O, Acar A H, Öztürk S A, Malkoç S
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Afyon Kocatepe University, 03030 Afyonkarahisar, Turkey.
Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, İnönü University, Malatya, Turkey.
Niger J Clin Pract. 2017 Dec;20(12):1531-1536. doi: 10.4103/1119-3077.181400.
The aim of the present study was to assess whether the use of platelet-rich fibrin (PRF) decreased the pain, swelling, and trismus levels of postoperative third molar surgery.
In a double-blinded, split-mouth randomized study, thirty patients (6 male/24 female, mean age 20.32 years) with bilateral symmetric impacted third molars were enrolled in this study to receive surgery. The PRF mass was randomly placed in one of the extraction sockets, whereas the other socket was left without treatment. The outcome variables were pain, maximum mouth opening (trismus), swelling (edema), and the presence of dry socket which were measured using a 10-point visual analog scale, manual calipers, and 3dMD facial imaging system which was used for the 1st time in the third molar surgery.
Statistical analyses revealed that there were no significant differences between the control and study groups regarding postoperative pain, swelling, and trismus (P > 0.05).
The results of this study suggest that PRF was not observed to have a positive effect on postoperative discomfort, so even though, PRF is presumed to have positive effects on healing and recovery processes.
本研究旨在评估使用富血小板纤维蛋白（PRF）是否能降低术后第三磨牙手术的疼痛、肿胀和牙关紧闭程度。
在一项双盲、双侧随机研究中，30例双侧对称阻生第三磨牙患者（6例男性/24例女性，平均年龄20.32岁）纳入本研究接受手术。将PRF块随机置于一侧拔牙窝，另一侧拔牙窝不做处理。观察指标包括疼痛、最大开口度（牙关紧闭）、肿胀（水肿）以及干槽症的发生情况，分别采用10分视觉模拟量表、手动卡尺和3dMD面部成像系统进行测量，3dMD面部成像系统首次应用于第三磨牙手术。
统计分析显示，对照组和研究组在术后疼痛、肿胀和牙关紧闭方面无显著差异（P>0.05）。
本研究结果表明，未观察到PRF对术后不适有积极影响，尽管PRF被认为对愈合和恢复过程有积极作用。
