沙特心血管疾病患者非处方药的使用情况
The utilization of nonprescription medications in Saudi patients with cardiovascular diseases.
作者信息
Shorog Eman M, Alburikan Khalid A
机构信息
Department of Clinical Pharmacy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia.
College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
出版信息
Saudi Pharm J. 2018 Jan;26(1):120-124. doi: 10.1016/j.jsps.2017.10.003. Epub 2017 Oct 3.
BACKGROUND
Cardiovascular diseases (CVDs) are the most common cause of disease-related death in Saudi Arabia. The incidence of CVDs continues to increase, presenting a major health care problem. Nonprescription medications are widely used by patients with CVD and may cause adverse drug events, either by worsening the disease or by harmfully interacting with prescribed medications. We investigated the patterns of nonprescription medication utilization and the factors associated with their use in patients with CVD.
METHODS
This was a cross-sectional study conducted at the Cardiology Clinics of an academic tertiary health care center. Participants were asked about their sociodemographic characteristics, medical history and frequency of using nonprescription medications including over-the-counter (OTC) products, dietary supplements, and herbal products. Moreover, we investigated the participants' sources of information about nonprescription medications. Multivariate logistic regression analysis was conducted to examine the predictors of nonprescription medication use.
RESULTS
A total of 209 participants were interviewed. The mean age of the participants was 56 ± 15 years, and 110 (52.6%) were female. Of the 209 participants, 116 (55%) reported routine use of nonprescription medications. Black seeds and garlic were the most frequently used herbal products. Acetaminophen, cold/cough remedies, and ibuprofen were the most commonly reported OTC drugs. Of the surveyed patients, 54 (46.5%) used nonprescription medications to manage cardiovascular conditions specifically. Compared with other comorbidities, diabetes mellitus was associated with a higher use of nonprescription medications.
CONCLUSION
In patients with CVD, the routine use of nonprescription medications was common for a number of reasons. Health care providers should proactively discuss nonprescription use with their CVD patients to avoid potential harmful outcomes.
背景
心血管疾病（CVDs）是沙特阿拉伯与疾病相关死亡的最常见原因。心血管疾病的发病率持续上升，这是一个重大的医疗保健问题。心血管疾病患者广泛使用非处方药，这些药物可能会导致不良药物事件，要么使病情恶化，要么与处方药发生有害相互作用。我们调查了心血管疾病患者非处方药的使用模式及其使用相关因素。
方法
这是一项在一家学术性三级医疗保健中心的心脏病诊所进行的横断面研究。询问了参与者的社会人口学特征、病史以及使用非处方药（包括非处方（OTC）产品、膳食补充剂和草药产品）的频率。此外，我们调查了参与者获取非处方药信息的来源。进行多变量逻辑回归分析以检查非处方药使用的预测因素。
结果
共采访了209名参与者。参与者的平均年龄为56±15岁，其中110名（52.6%）为女性。在209名参与者中，116名（55%）报告经常使用非处方药。黑种草籽和大蒜是最常用的草药产品。对乙酰氨基酚、感冒/咳嗽药和布洛芬是最常报告的非处方药物。在接受调查的患者中，54名（46.5%）使用非处方药专门治疗心血管疾病。与其他合并症相比，糖尿病与更高的非处方药使用率相关。
结论
在心血管疾病患者中，由于多种原因，经常使用非处方药的情况很常见。医疗保健提供者应主动与心血管疾病患者讨论非处方药的使用，以避免潜在的有害后果。
Zotero 插件