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双极经尿道前列腺剜除术:它是否已准备好取代经尿道前列腺电切术?

Bipolar transurethral enucleation and resection of the prostate: Whether it is ready to supersede TURP?

作者信息

Xu Peng, Xu Abai, Chen Binshen, Zheng Shaobo, Xu Yawen, Li Hulin, Shen Haiyan, Liu Chunxiao

机构信息

Department of Urology, Zhujiang Hospital, Southern Medical University, Guangzhou, China.

出版信息

Asian J Urol. 2018 Jan;5(1):48-54. doi: 10.1016/j.ajur.2017.12.001. Epub 2017 Dec 8.

Abstract

OBJECTIVE

According to the EAU Guidelines, transurethral resection of the prostate (TURP) has so far still been considered as the gold standard for surgical treatment for patients with obstructing clinical benign prostate hyperplasia (BPH). However, its relatively high rate of complications and postoperative recurrence necessitates further modification and innovation on the surgery technique. We reported the patient outcomes with our technique.

METHODS

We retrospectively analyzed 52 patients with obstructing clinical BPH who underwent bipolar transurethral enucleation and resection of the prostate (B-TUERP) between March 2015 and September 2015. Pre- and perioperative parameters were obtained from medical charts. Postoperative follow-ups were administrated at 1, 3, 6, 12 and 24 month(s) after surgery, respectively.

RESULTS

All the operations were performed successfully with a mean operative time of 43.1 min and an average tissue removal rate of 74.7%. Q was significantly improved immediately after surgery, followed by a continuous improvement throughout the follow-ups. Following a steep decrease in mean prostate specific antigen (PSA) and post void residual (PVR) observed within the first half year after surgery, the serum PSA was then maintained at a constant level of 0.61 ng/mL. Temporary urinary retention was found in four cases (7.7%). Stress urinary incontinence occurred in five patients (9.6%), with the condition resolved in 1-2 weeks without extra treatment. Urethral strictures and bladder neck contractures, as the most commonly observed long-term complications, developed in four patients (7.7%). No recurrence was found during 2 years of follow-ups. An improvement in International Index of Erectile Function (IIEF-5) scores was witnessed in 17 patients preoperatively with normal sexual function during the first 6 months after surgery, and sustained throughout the 24-month period.

CONCLUSIONS

Enucleation reflects an improvement on surgical technique in many ways with a need for surgical equipment that can be broadly accessible in clinical practice. Currently, bipolar resection is a commonly employed procedure in clinical settings, and its similarity shared with bipolar enucleation technique warrants a quick learning of B-TUERP by urologists. Based on these findings, we believe that the substitution of TURP by TUERP as the gold standard for prostate endoscopic procedure can be expected in the future.

摘要

目的

根据欧洲泌尿外科学会(EAU)指南,经尿道前列腺切除术(TURP)至今仍被视为梗阻性临床良性前列腺增生(BPH)患者手术治疗的金标准。然而,其相对较高的并发症发生率和术后复发率使得手术技术有必要进一步改进和创新。我们报告了采用我们的技术治疗患者的结果。

方法

我们回顾性分析了2015年3月至2015年9月期间接受双极经尿道前列腺剜除术(B-TUERP)的52例梗阻性临床BPH患者。术前和围手术期参数从病历中获取。术后分别在术后1、3、6、12和24个月进行随访。

结果

所有手术均成功完成,平均手术时间为43.1分钟,平均组织切除率为74.7%。术后Q值立即显著改善,随后在整个随访过程中持续改善。术后上半年平均前列腺特异性抗原(PSA)和残余尿量(PVR)急剧下降,之后血清PSA维持在0.61 ng/mL的恒定水平。4例(7.7%)出现暂时性尿潴留。5例(9.6%)患者发生压力性尿失禁,无需额外治疗,1-2周内症状缓解。4例(7.7%)患者出现尿道狭窄和膀胱颈挛缩,这是最常见的长期并发症。随访2年未发现复发。术前性功能正常的17例患者术后前6个月国际勃起功能指数(IIEF-5)评分有所改善,并在24个月期间持续改善。

结论

剜除术在许多方面反映了手术技术的改进,需要临床实践中广泛可用的手术设备。目前,双极切除术是临床常用的手术方法,其与双极剜除术技术的相似性使泌尿外科医生能够快速学习B-TUERP。基于这些发现,我们相信未来有望用TUERP替代TURP作为前列腺内镜手术的金标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27a2/5780288/516e60551215/gr1.jpg

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