Urrutia Julio, Besa Pablo, Lobos Daniel, Campos Mauricio, Arrieta Cristobal, Andia Marcelo, Uribe Sergio
Department of Orthopaedic Surgery, School of Medicine, Pontificia Universidad Catolica de Chile, Marcoleta 352, Santiago, Chile.
Biomedical Imaging Center, Pontificia Universidad Catolica de Chile, Santiago, Chile.
Skeletal Radiol. 2018 Jul;47(7):955-961. doi: 10.1007/s00256-018-2880-1. Epub 2018 Jan 29.
To determine the association of paraspinal muscles and psoas relative cross-sectional area (RCSA) and fat signal fraction (FSF) with sex, age, and intervertebral disc degeneration (IDD) in symptomatic patients.
We retrospectively evaluated 80 adult patients with spinal symptoms using T2-weighted magnetic resonance images. We determined RCSA and FSF of the paraspinal muscles (erector spinae and multifidus) and psoas from L1-L2 to L5-S1; we determined IDD using the Pfirrmann classification. We compared differences in muscle RCSA and FSF based on sex and IDD, and we correlated age and IDD with RCSA and FSF. Using multivariate linear regression analyses, we determined the impact of sex, age, and IDD on RCSA and FSF.
Men exhibited larger psoas RCSA but not larger paraspinal muscles RCSA than women. Women had larger FSF in the paraspinal muscles and psoas. Increasing IDD was associated with larger FSF if ≥2 Pfirrmann grades were observed. IDD correlated with FSF of the paraspinal muscles, and age correlated with FSF of the paraspinal muscles and psoas. IDD was less consistently correlated with RCSA, but age correlated negatively with RCSA of all three muscles. Linear regression analyses demonstrated that sex, age, and IDD were each independently associated with FSF of the paraspinal muscles; additionally, sex and age, but not IDD, were associated with psoas FSF. RCSA was less consistently influenced by these three variables.
Sex, age, and IDD are independently associated with paraspinal muscles FSF; only sex and age influence psoas FSF.
确定有症状患者的椎旁肌和腰大肌相对横截面积（RCSA）及脂肪信号分数（FSF）与性别、年龄和椎间盘退变（IDD）之间的关联。
我们使用T2加权磁共振成像对80例有脊柱症状的成年患者进行了回顾性评估。我们测定了从L1-L2至L5-S1节段的椎旁肌（竖脊肌和多裂肌）及腰大肌的RCSA和FSF；我们使用Pfirrmann分类法确定IDD。我们比较了基于性别和IDD的肌肉RCSA和FSF差异，并将年龄和IDD与RCSA和FSF进行了相关性分析。通过多变量线性回归分析，我们确定了性别、年龄和IDD对RCSA和FSF的影响。
男性腰大肌的RCSA比女性大，但椎旁肌的RCSA不比女性大。女性椎旁肌和腰大肌的FSF更大。如果观察到≥2个Pfirrmann分级，IDD增加与更大的FSF相关。IDD与椎旁肌的FSF相关，年龄与椎旁肌和腰大肌的FSF相关。IDD与RCSA的相关性不太一致，但年龄与所有三块肌肉的RCSA呈负相关。线性回归分析表明，性别、年龄和IDD均与椎旁肌的FSF独立相关；此外，性别和年龄与腰大肌的FSF相关，而IDD与之无关。这三个变量对RCSA的影响不太一致。
性别、年龄和IDD与椎旁肌的FSF独立相关；只有性别和年龄影响腰大肌的FSF。
