Chai Wei, Gong Fengyan, Zhang Wenlei, Wen Yan, Cui Lifeng
Department of Gynecology and Obstetrics Department of Interventional Therapy, The First Hospital of Jilin University, Changchun, Jilin, China.
Medicine (Baltimore). 2017 Nov;96(47):e8860. doi: 10.1097/MD.0000000000008860.
Multiple primary cancer (MPC) refers to tumors that occur in one or multiple organs within the same patient at the same time or at different periods. MPC often occurs in the head and neck, but is rarely reported in the female genital system.
In the present study, we report 2 rare cases that presented with tangible lower abdominal tumors.
Laboratory tests, pelvic ultrasound (US), computed tomography (CT), and fast histopathological examinations during surgery indicated a diagnosis of MPC.
The 2 patients all received radical resections of multiple tumors.
Postsurgical histopathological and immunohistochemical examinations further confirmed primary endometrial cancer and right ovarian cancer in Case 1, and primary cervical cancer and left ovarian cancer of Case 2. The 2 patients all recovered well without obvious complications.
Our study demonstrated that female genital MPC should be noted for patients with multiple genital tumors. In addition, accurately diagnosis and radical surgical treatment should be well performed.
多原发性癌（MPC）是指同一患者在同一时间或不同时期发生于一个或多个器官的肿瘤。MPC常发生于头颈部，但在女性生殖系统中鲜有报道。
在本研究中，我们报告了2例出现下腹部可触及肿物的罕见病例。
实验室检查、盆腔超声（US）、计算机断层扫描（CT）以及手术中的快速组织病理学检查提示诊断为MPC。
2例患者均接受了多肿瘤根治性切除术。
术后组织病理学和免疫组化检查进一步证实病例1为原发性子宫内膜癌和右卵巢癌，病例2为原发性宫颈癌和左卵巢癌。2例患者均恢复良好，无明显并发症。
我们的研究表明，对于患有多种生殖器肿瘤的患者，应注意女性生殖器MPC。此外，应做好准确诊断和根治性手术治疗。
