Gerasimova E N, Ozerova I N, Shcherbakova I A, Shal'nova S A, Levachev M M
Ter Arkh. 1986;58(1):55-60.
A comparative analysis of the fatty acid composition of phosphatidylcholines (PC) and sphingomyelins (SP) of lipoproteins (LP) of low and very low density was performed in the blood plasma of Eskimos (indigenous population of the Chukot Peninsula) in myocardial hypertrophy and in the control group as well as in the control group of Muscovites. Some characteristic features of the fatty acid composition of low density LP PC and SP were revealed in Eskimos in myocardial hypertrophy. The role of changes in the transport of fatty acids of low density LP PC and SP of the blood plasma in the myocyte membrane liquidity as well as in the synthesis of biologically active prostacyclin revealed in myocardial hypertrophy was discussed.
对楚科奇半岛原住民爱斯基摩人、心肌肥厚患者及对照组以及莫斯科人对照组的血浆中低密度和极低密度脂蛋白(LP)的磷脂酰胆碱(PC)和鞘磷脂(SP)的脂肪酸组成进行了比较分析。在心肌肥厚的爱斯基摩人中发现了低密度LP的PC和SP脂肪酸组成的一些特征。讨论了血浆中低密度LP的PC和SP的脂肪酸转运变化在心肌肥厚中所揭示的心肌细胞膜流动性以及生物活性前列环素合成中的作用。