Suppr超能文献

经口气管冲洗对患有呼吸道疾病犬类呼吸力学的影响。

Effect of transoral tracheal wash on respiratory mechanics in dogs with respiratory disease.

作者信息

Vaught Meghan E, Rozanski Elizabeth A, deLaforcade Armelle M

机构信息

Section of Critical Care, Cummings School of Veterinary Medicine, Tufts University, North Grafton, Massachusetts 01536, USA.

出版信息

Can J Vet Res. 2018 Jan;82(1):75-79.

Abstract

The purpose of this study was to determine the impact of a transoral tracheal wash (TOTW) on respiratory mechanics in dogs and to describe the use of a critical care ventilator (CCV) to determine respiratory mechanics. Fourteen client-owned dogs with respiratory diseases were enrolled. Respiratory mechanics, including static compliance (C) and static resistance (R), were determined before and after TOTW. Pre- and post-wash results were compared, with a -value of < 0.05 considered significant. The mean ± standard deviation (SD) value of C pre-TOTW was 1.59 ± 0.94 mL/cmHO/kg while the mean ± SD of C post-TOTW was 1.29 ± 0.71 mL/cmHO/kg ( = 0.045). The median R was not significantly different pre- and post-wash. The transoral tracheal wash altered respiratory mechanics, as observed by a reduction in C, presumably due to airway flooding and collapse. While no long-lasting effects were noted in these clinical patients, this effect should be considered when performing TOTW on dogs with respiratory diseases. Respiratory mechanics testing using a CCV was feasible and may be a useful clinical testing approach.

摘要

本研究的目的是确定经口气管冲洗(TOTW)对犬类呼吸力学的影响,并描述使用重症监护呼吸机(CCV)来确定呼吸力学。招募了14只患有呼吸道疾病的宠物犬。在TOTW前后测定呼吸力学,包括静态顺应性(C)和静态阻力(R)。比较冲洗前后的结果,P值<0.05被认为具有显著性。TOTW前C的平均值±标准差(SD)为1.59±0.94 mL/cmH₂O/kg,而TOTW后C的平均值±SD为1.29±0.71 mL/cmH₂O/kg(P = 0.045)。冲洗前后R的中位数无显著差异。经口气管冲洗改变了呼吸力学,表现为C降低,推测是由于气道充盈和塌陷所致。虽然在这些临床患者中未观察到长期影响,但在对患有呼吸道疾病的犬进行TOTW时应考虑这种影响。使用CCV进行呼吸力学测试是可行的,可能是一种有用的临床测试方法。

相似文献

7
Pulmonary function testing in small animals.小动物的肺功能测试。
Clin Tech Small Anim Pract. 1999 Nov;14(4):237-41. doi: 10.1016/S1096-2867(99)80017-6.

本文引用的文献

3
Transtracheal wash and bronchoalveolar lavage.经气管冲洗和支气管肺泡灌洗。
Top Companion Anim Med. 2013 Aug;28(3):97-102. doi: 10.1053/j.tcam.2013.06.003.
10
Airway physiology and clinical function testing.气道生理学与临床功能测试
Vet Clin North Am Small Anim Pract. 2007 Sep;37(5):829-43, v. doi: 10.1016/j.cvsm.2007.05.013.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验