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全麻下犬肺泡复张手法对肺泡通气、气体交换和呼吸力学的影响。

Alveolar recruiting maneuver in dogs under general anesthesia: effects on alveolar ventilation, gas exchange, and respiratory mechanics.

机构信息

Dipartimento delle Emergenze e dei Trapianti d'Organo, Sezione di Chirurgia Veterinaria, Università degli Studi di Bari, Bari, Italy.

出版信息

Vet Res Commun. 2010 Jun;34 Suppl 1:S131-4. doi: 10.1007/s11259-010-9405-2.

Abstract

The aim of this study was to evaluate the effects of a recruiting maneuver (RM) on lung aeration, gas exchange, and respiratory mechanics during general anesthesia in mechanically ventilated dogs. A thoracic computed tomography (CT) scan, an arterial blood sample, and measurement of respiratory mechanics were performed 10 min before (baseline) and both 5 and 30 min after a vital capacity RM in 10 dogs under general anesthesia. The RM was performed by inflating the lung at 40 cm H(2)O for 20 s. Lung aeration was estimated by analyzing the radiographic attenuation of the CT images. Lung aeration and gas exchange improved significantly 5 min after the RM compared to baseline and returned to values similar to baseline by 30 min. Static lung compliance was not significantly affected by the RM. An RM induces a temporary improvement in lung function in healthy dogs under general anesthesia.

摘要

本研究旨在评估在机械通气的狗全麻期间,一项募集手法(RM)对肺通气、气体交换和呼吸力学的影响。全麻下的 10 只狗在 RM 前 10 分钟(基线)和 RM 后 5 分钟和 30 分钟分别进行了一次胸部 CT 扫描、动脉血样本采集和呼吸力学测量。RM 通过将肺充气至 40cmH2O 持续 20s 来实现。通过分析 CT 图像的放射衰减来评估肺通气。RM 后 5 分钟,肺通气和气体交换与基线相比显著改善,30 分钟时恢复到与基线相似的值。RM 对静态肺顺应性没有显著影响。RM 可在健康狗全麻期间暂时改善肺功能。

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