Center for Epidemiology and Prevention in Oncology, Città della Salute e della Scienza, Torino, Italy.
Epidemiology Department, Local Health Unit TO3, Piedmont Region, Grugliasco, Torino, Italy.
Int J Public Health. 2018 Apr;63(3):325-335. doi: 10.1007/s00038-018-1076-8. Epub 2018 Jan 30.
The aim of this study was to assess social inequalities in overall mortality in a representative sample of the Italian population, and to evaluate the contribution of behavioural and metabolic risk (BMF) factors to these inequalities.
85,308 participants aged 25-74 years from the Italian Longitudinal Study were included in the study population and followed up for mortality (1999-2012). Level of education was used as a proxy for socioeconomic status. The contribution of BMF was estimated assessing the attenuation of the risk by education produced by the inclusion of BMF in regression model.
Men with the lowest education had 62% and women had 57% greater risk of dying than those with the highest education. Among men, adjustment for BMF produced an attenuation of the mortality risk between extreme classes of education by 22%, while among women the risk attenuation was 7%.
Large educational differences in mortality were observed for both men and women. BMF reduced by approximately 20% differences in mortality relative risk between extreme classes of education in men. In contrast, a very low contribution was observed in women.
本研究旨在评估意大利代表性人群样本中总体死亡率的社会不平等，并评估行为和代谢风险（BMF）因素对这些不平等的贡献。
85308 名年龄在 25-74 岁的意大利纵向研究参与者被纳入研究人群，并随访至死亡（1999-2012 年）。教育水平被用作社会经济地位的替代指标。通过在回归模型中纳入 BMF 来评估 BMF 对教育风险的衰减程度，来估计 BMF 的贡献。
受教育程度最低的男性死亡风险比受教育程度最高的男性高 62%，女性高 57%。在男性中，调整 BMF 后，极端教育类别之间的死亡率风险降低了 22%，而在女性中，风险降低了 7%。
男性和女性的死亡率都存在较大的教育差异。BMF 降低了男性极端教育类别之间死亡率相对风险差异的约 20%。相比之下，在女性中观察到的贡献非常低。
