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急性 I 型主动脉夹层手术不切除主动脉入口部位会导致主动脉重塑不良。

Surgery for acute Type I aortic dissection without resection of supra-aortic entry sites leads to unfavourable aortic remodelling.

机构信息

Department of Cardiovascular Surgery, Gangnam Severance Hospital, Seoul, Korea.

Department of Interventional Radiology, Gangnam Severance Hospital, Seoul, Korea.

出版信息

Eur J Cardiothorac Surg. 2018 Jul 1;54(1):34-41. doi: 10.1093/ejcts/ezx504.

Abstract

OBJECTIVES

This study aimed to evaluate the impact of remnant re-entries in arch branches on postoperative change in the aortic arch and descending aortic diameters and the rate of major adverse aortic events.

METHODS

Between January 2010 and December 2016, 249 patients underwent surgery for acute Type I aortic dissection. Patients who underwent total arch replacement, had Marfan syndrome or had intramural haematoma were excluded. Seventy-two patients with predischarge and follow-up computed tomography scans were enrolled. Patients with and without re-entries in the arch branches after surgery were assigned to the supra-aortic entry (SAE, n = 21) and no supra-aortic entry (n = 51) groups, respectively. Diameters were measured at 7 levels: the innominate artery, left common carotid artery, left subclavian artery, 20 mm distal to the left subclavian artery, pulmonary artery bifurcation, coeliac axis and maximal diameter of the descending thoracic aorta.

RESULTS

Growth rates at the levels of the pulmonary artery bifurcation and 20 mm distal to the left subclavian artery were significantly higher in the SAE group than in the no supra-aortic entry group. The rate of freedom from major adverse aortic events (annual growth >5 mm or maximal diameter of the descending thoracic aorta >50 mm) at 5 years was significantly higher in the no supra-aortic entry group than in the SAE group.

CONCLUSIONS

Remnant SAE leads to unfavourable aortic remodelling after acute Type I aortic dissection repair.

摘要

目的

本研究旨在评估弓部分支残端再入口对主动脉弓和降主动脉直径术后变化以及主要不良主动脉事件发生率的影响。

方法

2010 年 1 月至 2016 年 12 月,共有 249 例急性 I 型主动脉夹层患者接受手术治疗。排除行全主动脉弓置换术、马凡综合征或壁内血肿的患者。共纳入 72 例有出院前和随访计算机断层扫描的患者。将手术后弓部分支有和无再入口的患者分别分为升主动脉入口组(SAE,n=21)和无升主动脉入口组(n=51)。在 7 个部位测量直径:无名动脉、左颈总动脉、左锁骨下动脉、左锁骨下动脉 20mm 处、肺动脉分叉、腹腔干和降胸主动脉最大直径。

结果

SAE 组在肺动脉分叉和左锁骨下动脉 20mm 处的生长率明显高于无升主动脉入口组。无升主动脉入口组 5 年免于主要不良主动脉事件(每年生长>5mm 或降胸主动脉最大直径>50mm)的比例明显高于 SAE 组。

结论

急性 I 型主动脉夹层修复后,残留的 SAE 导致主动脉重塑不良。

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