Tausk F A, McCutchan J A, Schreiber R D, Spechko P, Gigli I
Biosci Rep. 1986 Jan;6(1):81-6. doi: 10.1007/BF01145182.
The expression of C3b receptors (CR1) on erythrocytes of gay men at various levels of risk for AIDS was studied. Fourty-nine heterosexual male controls had a mean (X) +/- standard deviation of 516 +/- 136 CR1 per erythrocyte (CR1-3); 17 asymptomatic gay men had X = 423 +/- 156, 16 gay men with one AIDS-related complex (ARC) symptom or sign had X = 342 +/- 154, 9 patients with ARC had X = 252 +/- 76, and 14 gay men with AIDS had X = 173 +/- 76 CR1-E. The patients with ARC and AIDS had a highly significant decrease in CR1-E when compared with normal individuals (p = less than 0.001) and studies of families of 4 AIDS patients suggest that this defect is acquired.
对处于不同艾滋病风险水平的男同性恋者红细胞上C3b受体（CR1）的表达进行了研究。49名异性恋男性对照组每红细胞（CR1-3）的CR1平均（X）±标准差为516±136；17名无症状男同性恋者X = 423±156，16名有一项艾滋病相关综合征（ARC）症状或体征的男同性恋者X = 342±154，9名ARC患者X = 252±76，14名艾滋病男同性恋者X = 173±76 CR1-E。与正常个体相比，ARC患者和艾滋病患者的CR1-E显著降低（p＜0.001），对4名艾滋病患者家庭的研究表明这种缺陷是后天获得的。
