Yélamos Oriol, Ros Sandra, Puig Lluís
Department of Dermatology, Hospital de la Santa Creu i Sant Pau - Universitat Autònoma de Barcelona, Barcelona, Catalonia, Spain.
Psoriasis (Auckl). 2015 Jul 17;5:109-115. doi: 10.2147/PTT.S54070. eCollection 2015.
Psoriasis is a frequent inflammatory disease with a chronic and relapsing course. Therefore, patients with psoriasis are likely to undergo different treatments for long periods of time. Traditionally, therapies used in psoriasis have been associated with poor levels of adherence due to the complexity of the regimens and the poor results obtained with the topical therapies. These poor outcomes are associated with high levels of frustration and anxiety, which decrease adherence and worsen the disease. With the recent introduction of highly efficacious biologic therapies, patients can achieve very good and prolonged responses. However, most patients with psoriasis have mild disease and may be treated with skin-directed therapies. Therefore, it is important to develop strategies to improve adherence in order to achieve better outcomes, and to improve the overall quality of life. Hence, acknowledging the causes of nonadherence is crucial for implementing these strategies. In this summary, we review the causes of nonadherence, and we provide behavioral strategies in order to improve adherence and, ultimately, the outcome of patients with psoriasis.
银屑病是一种常见的炎症性疾病，病程呈慢性且易复发。因此，银屑病患者可能需要长时间接受不同的治疗。传统上，用于治疗银屑病的疗法因治疗方案复杂以及局部治疗效果不佳，导致患者依从性较差。这些不佳的治疗结果与高度的沮丧和焦虑相关，进而降低依从性并使病情恶化。随着近期高效生物疗法的引入，患者能够获得非常好且持久的疗效。然而，大多数银屑病患者病情较轻，可能采用针对皮肤的疗法进行治疗。因此，制定提高依从性的策略以取得更好的治疗效果并改善整体生活质量非常重要。因此，认识到不依从的原因对于实施这些策略至关重要。在本综述中，我们回顾了不依从的原因，并提供行为策略以提高依从性，最终改善银屑病患者的治疗结果。
