Franken Sylvie M, Vierstra Carlijn L, Rustemeyer Thomas
Department of Dermatology, VU University Medical Centre, Amsterdam, the Netherlands.
Psoriasis (Auckl). 2016 May 18;6:55-64. doi: 10.2147/PTT.S81958. eCollection 2016.
Although the treatment burden for phototherapy in the outpatient setting is considerable, prescription of home-based phototherapy has not been instigated. Home-based phototherapy seems more patient friendly in terms of avoiding the thrice-weekly hospital visits. So why are most treatments still given in a hospital setting? Is home-based treatment less effective? Are there financial barriers? Is the treatment not available? To answer these questions, a literature search was done.
A literature search of PubMed, Embase, and Cochrane Library databases was performed, using the search terms "psoriasis" and "phototherapy". Selection was based on two rounds; the first round involved screening the title and abstract of all records and second involved evaluating the full text of the remaining articles for eligibility according to inclusion and exclusion criteria.
In total, 23 publications were included with consensus of both researchers. Overall, the patients reported being very satisfied with home-based phototherapy. Results regarding effectivity in terms of improvement from disease severity and in quality of life were variable but generally positive. Reasons for reluctance varied from medicolegal and social aspects to lack of reimbursement and unfamiliarity on the side of the prescriber.
In the treatment for psoriasis, home-based phototherapy is as effective and safe as phototherapy in an outpatient setting. Patients were more satisfied with home-based phototherapy. Factors that negatively influence the prescription of or choice for home-based phototherapy can be summarized in terms of lack of control, lack of knowledge, and lack of a good reimbursement system.
尽管门诊光疗的治疗负担相当大,但家庭光疗的处方尚未得到推广。从避免每周三次的医院就诊来看,家庭光疗似乎对患者更友好。那么,为什么大多数治疗仍在医院进行呢?是家庭治疗效果较差吗?存在经济障碍吗?还是无法获得这种治疗?为了回答这些问题,我们进行了文献检索。
使用“银屑病”和“光疗”作为检索词,对PubMed、Embase和Cochrane图书馆数据库进行文献检索。筛选分两轮进行;第一轮涉及筛选所有记录的标题和摘要,第二轮涉及根据纳入和排除标准评估其余文章的全文是否符合条件。
两位研究人员达成共识,共纳入23篇出版物。总体而言,患者对家庭光疗非常满意。从疾病严重程度改善和生活质量方面来看,有效性结果各不相同,但总体呈积极趋势。不愿采用家庭光疗的原因从法医学和社会层面到缺乏报销以及开处方者不熟悉等各有不同。
在银屑病治疗中,家庭光疗与门诊光疗一样有效且安全。患者对家庭光疗更满意。对家庭光疗处方或选择产生负面影响的因素可归纳为缺乏控制、缺乏知识以及缺乏良好的报销系统。