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英国泌尿外科学会(BAUS)2014/2015 年根治性前列腺切除术审核——按中心和外科医生手术量更新当前实践和结果

The British Association of Urological Surgeons (BAUS) radical prostatectomy audit 2014/2015 - an update on current practice and outcomes by centre and surgeon case-volume.

机构信息

Exeter Surgical Health Services Research Unit, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.

British Association of Urological Surgeons, Bristol, UK.

出版信息

BJU Int. 2018 Jun;121(6):886-892. doi: 10.1111/bju.14156. Epub 2018 Feb 26.

Abstract

OBJECTIVES

To describe contemporary radical prostatectomy (RP) practice using the British Association of Urological Surgeons (BAUS) data and audit project and to observe differences in practice in relation to surgeon or centre case-volume.

PATIENTS AND METHODS

Data on 13 920 RP procedures performed by 179 surgeons across 86 centres were recorded on the BAUS data and audit platform between 1 January 2014 and 31 December 2015. This equates to ~95% of total RPs performed over this period when compared to Hospital Episode Statistics (HES) data. Centre case-volumes were categorised as 'high' (>200), 'medium' (100-200) and 'low' (<100); surgeon case-volumes were categorised as 'high' (>100) and 'low' (<100). Differences in surgical practice and selected outcome measures were observed between groups. All data and volume categories were for the combined 2-year period.

RESULTS

The median number of RPs performed over the 2-year period was 63.5 per surgeon and 164 per centre. Overall, surgical approach was robot-assisted laparoscopic RP (RALP) in 65%, laparoscopic RP (LRP) in 23%, and open RP (ORP) in 12%. The dominant approach in high-case-volume centres and by high-case-volume surgeons was RALP (74.3% and 69.2%, respectively). There was a greater percentage of ORPs reported by low-volume surgeons and centres when compared to higher volume equivalents. In all, 51.6% of all patients in this series underwent RP in high-case-volume centres using robot-assisted surgery (RAS). High-case-volume surgeons performed nerve-sparing (NS) procedures on 57.3% of their cases; low-volume surgeons performing NS on 48.2%. Overall, lymph node dissection (LND) rates were very similar across the groups. An 'extended' LND was more commonly performed in high-volume centres (22.1%). The median length of stay (LOS) was lowest in patients undergoing RALP at high-volume centres (1 day) and highest in ORP across all volume categories (3-4 days). Reported pT2 positive surgical margin (PSM) rate varied by technique, centre volume, and surgeon volume. In general, observed PSM rates were lower when RALP was the surgical approach (14.4%) and when high-volume surgeons were compared to low-volume surgeons (13.6% vs 17.7%). Transfusion rates were highest in ORP across all centres and surgeons (2.96-4.49%) compared to techniques using a minimally-invasive approach (0.25-2.41%). Training cases ranged from 0.5% in low-volume centres to 6.0% in high-volume centres.

CONCLUSIONS

Compliance with data registration for centres and surgeons performing RP is high in the present series. Most RPs were performed in high-case-volume centres and by high-case-volume surgeons, with the most common approaches being minimally invasive and specifically RAS. High-case-volume centres and surgeons reported higher rates of extended LND and training cases. Higher-case-volume surgeons reported lower pT2 PSM rates, whilst the most marked differences in transfusion rates and LOS were seen when ORP was compared to minimally invasive approaches. Caution must be applied when interpreting these differences on the basis of this being registry data - causality cannot be assumed.

摘要

目的

利用英国泌尿外科学会 (BAUS) 的数据和审计项目描述当代根治性前列腺切除术 (RP) 的实践,并观察与外科医生或中心病例量相关的实践差异。

方法

在 2014 年 1 月 1 日至 2015 年 12 月 31 日期间,179 名外科医生在 86 个中心共记录了 13920 例 RP 手术的数据,这些数据都记录在 BAUS 数据和审计平台上。与医院发病统计数据 (HES) 相比,这相当于同期进行的 RP 总量的~95%。中心病例量分为“高” (>200)、“中” (100-200) 和“低” (<100);外科医生病例量分为“高” (>100) 和“低” (<100)。观察了各组之间手术实践和选定的结果指标的差异。所有数据和容量类别均为两年期的综合数据。

结果

两年期间,外科医生平均进行 63.5 例 RP,中心平均进行 164 例 RP。总体而言,手术方法为机器人辅助腹腔镜 RP (RALP) 占 65%,腹腔镜 RP (LRP) 占 23%,开放 RP (ORP) 占 12%。高病例量中心和高病例量外科医生的主要方法是 RALP (分别为 74.3%和 69.2%)。与高容量等效值相比,低容量外科医生和中心报告的 ORP 比例更高。在本系列中,所有患者中有 51.6%在高病例量中心接受机器人辅助手术 (RAS) 的 RP。高病例量外科医生对 57.3%的病例进行神经保留 (NS) 手术;低容量外科医生对 48.2%的病例进行 NS。总体而言,各组的淋巴结清扫 (LND) 率非常相似。高容量中心更常进行“扩展” LND (22.1%)。高容量中心接受 RALP 的患者的中位住院时间 (LOS) 最短 (1 天),所有容量类别中接受 ORP 的患者的 LOS 最高 (3-4 天)。报告的 pT2 阳性切缘 (PSM) 率因技术、中心容量和外科医生容量而异。一般来说,当 RALP 是手术方法时 (14.4%),当高容量外科医生与低容量外科医生相比时 (13.6% vs 17.7%),观察到的 PSM 率较低。所有中心和外科医生的输血率最高 (ORP 为 2.96-4.49%),而使用微创方法的技术为 0.25-2.41%。低容量中心的培训病例数从 0.5%到高容量中心的 6.0%不等。

结论

在本系列中,进行 RP 的中心和外科医生的数据登记符合率很高。大多数 RP 都是在高病例量中心和高病例量外科医生中进行的,最常见的方法是微创和特定的 RAS。高病例量中心和外科医生报告了更高的扩展 LND 和培训病例数。高病例量外科医生报告的 pT2 PSM 率较低,而 ORP 与微创方法相比,输血率和 LOS 的差异最为明显。在基于此为登记数据解释这些差异时必须谨慎——不能假设因果关系。

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