Medical University Innsbruck, Department of Internal Medicine IV, Innsbruck, Tyrol, Austria.
Medical University Innsbruck, Department of Internal Medicine IV, Innsbruck, Tyrol, Austria.
Kidney Int. 2018 Feb;93(2):308-310. doi: 10.1016/j.kint.2017.10.026.
The incidence and prevalence of diabetic kidney disease is increasing. Observational and interventional studies suggest that the pathophysiology varies between individuals and within a patient over time. There is a huge clinical need to describe the molecular processes that modulate diabetic kidney disease. "Omics" experiments combined with bioinformatical analysis tools might allow for profiling of patients on an individual or at least group level to improve prediction of prognosis and guide targeted therapy.
糖尿病肾病的发病率和患病率正在上升。观察性和干预性研究表明，个体之间以及个体随时间的病理生理学变化存在差异。临床上迫切需要描述调节糖尿病肾病的分子过程。“组学”实验结合生物信息学分析工具可能允许对个体或至少对群体水平的患者进行分析，以改善预后预测并指导靶向治疗。
