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一名年轻成年人患有颅内扩展的全脊髓少突胶质细胞瘤:病例报告及文献综述

Holocord oligodendroglioma with intracranial extension in a young adult: a case report and review of literature.

作者信息

Cruz Romulus Emmanuel H, De Roxas Ranhel C, Sales-Callangan Carmela Concepcion A, Jamora Roland Dominic G

机构信息

Department of Neurosciences, College of Medicine - Philippine General Hospital, University of the Philippines Manila, Taft Avenue, Ermita, Manila, 1000, Philippines.

出版信息

CNS Oncol. 2018 Jan;7(1):1-5. doi: 10.2217/cns-2017-0012. Epub 2018 Feb 2.

Abstract

Widespread primary spinal oligodendrogliomas are a rare variety of tumors that usually affect children. Currently, there are only two adult cases reported worldwide. We report the first case of primary holocord oligodendroglioma with intracranial extension in a young adult female. The patient presented with a 4-month history of fluctuating hemiparesis of the left upper extremity eventually becoming quadriplegic after 1 month. Imaging findings revealed a contrast-enhancing holocord neoplasm spanning from the cervical region to the conus medullaris and with extension to the lower medulla. The patient succumbed to severe pneumonia after 1 month of admission. An autopsy was done and the histopathologic findings were consistent with oligodendroglioma.

摘要

广泛的原发性脊髓少突胶质细胞瘤是一种罕见的肿瘤类型,通常影响儿童。目前,全球仅报道了两例成人病例。我们报告了首例发生于年轻成年女性的原发性全脊髓少突胶质细胞瘤并伴有颅内扩展。该患者有4个月的左上肢波动性偏瘫病史,1个月后最终发展为四肢瘫痪。影像学检查结果显示,一个增强造影的全脊髓肿瘤,从颈椎区域延伸至脊髓圆锥,并延伸至延髓下部。患者入院1个月后死于重症肺炎。进行了尸检,组织病理学检查结果与少突胶质细胞瘤一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7efa/6001686/1632d449f926/cns-07-01-g1.jpg

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