Sujatha-Bhaskar Sarath, Alizadeh Reza F, Koh Christina, Inaba Colette, Jafari Mehraneh D, Carmichael Joseph C, Stamos Michael J, Pigazzi Alessio
Department of Surgery, University of California, Irvine School of Medicine, Irvine, California, USA.
Am Surg. 2017 Oct 1;83(10):1068-1073.
Emergent colonic disease has traditionally been managed with open procedures. Evaluation of recent trends suggests a shift toward minimally invasive techniques in this disease setting. The American College of Surgeons National Surgical Quality Improvement Program (NSQIP) targeted colectomy database from 2012 to 2014 was used to examine clinical data from patients who emergently underwent open colectomy (OC) and laparoscopic colectomy (LC). Multivariate regression was utilized to analyze preoperative characteristics and determine risk-adjusted outcomes with intent-to-treat and as-treated approach. Of 10,018 patients with emergent colonic operation, 90 per cent (9023) underwent OC whereas 10 per cent (995) underwent LC. Laparoscopic utilization increased annually, with LC composing 10.9 per cent of emergent colonic operations in 2014 compared with 9.3 per cent in 2012. Compared with LC, patients treated with OC had higher rates of overall morbidity (odds ratio 2.01, 95% confidence interval 1.74-2.34, P < 0.01) and 30-day mortality (odds ratio 1.79, 95% confidence interval 1.30-2.46, P < 0.01). Subset analysis of emergent patients without preoperative septic shock revealed consistent benefits with laparoscopy in overall morbidity, 30-day mortality, ileus, and surgical site infection. In select patients with hemodynamic stability, emergent LC appears to be a safe and beneficial operation. This study reflects the growing preference and utilization of minimally invasive techniques in emergent colonic operations.
传统上,急诊结肠疾病的治疗采用开放手术。对近期趋势的评估表明,在这种疾病情况下,治疗方式正朝着微创技术转变。利用美国外科医师学会国家外科质量改进计划(NSQIP)2012年至2014年的目标结肠切除术数据库,检查急诊接受开放结肠切除术(OC)和腹腔镜结肠切除术(LC)患者的临床数据。采用多因素回归分析术前特征,并通过意向性治疗和实际治疗方法确定风险调整后的结果。在10018例急诊结肠手术患者中,90%(9023例)接受了OC,而10%(995例)接受了LC。腹腔镜手术的使用率逐年上升,2014年LC占急诊结肠手术的10.9%,而2012年为9.3%。与LC相比,接受OC治疗的患者总体发病率(优势比2.01,95%置信区间1.74 - 2.34,P < 0.01)和30天死亡率(优势比1.79,95%置信区间1.30 - 2.46,P < 0.01)更高。对术前无感染性休克的急诊患者进行亚组分析显示,腹腔镜手术在总体发病率、30天死亡率、肠梗阻和手术部位感染方面均具有持续的益处。对于部分血流动力学稳定的患者,急诊LC似乎是一种安全且有益的手术。这项研究反映了微创技术在急诊结肠手术中越来越受到青睐和应用。