Rutgers New Jersey Medical School, 185 South Orange Avenue, Suite MSB G530, Newark, NJ, 07103, USA.
Department of Surgery, Division of Colorectal Surgery, Rutgers New Jersey Medical School, Newark, NJ, USA.
Updates Surg. 2020 Sep;72(3):835-844. doi: 10.1007/s13304-020-00803-9. Epub 2020 Jun 9.
Emergent colectomy is performed in thousands of Americans each year and carries significant morbidity and mortality. Although laparoscopy has gained favor in the elective setting, its impact on failure to rescue has not been studied on a population level for emergent colectomy. The purpose of this study was to compare failure to rescue following laparoscopic versus open colectomy in the emergency setting. This was a retrospective cohort study of The American College of Surgeons National Surgical Quality Improvement Program. Adult patients undergoing emergent colectomy between 2005 and 2018 were selected and stratified into laparoscopic or open surgery groups using the Current Procedural Terminology codes. Propensity matching was performed based on the demographic and comorbidity data. Main outcomes were failure to rescue, mortality, overall morbidity, individual complications, and length of hospital stay. After matching, 11,484 cases were included for analysis, of which 3829 were laparoscopic. Overall, open colectomy conferred higher odds of failure to rescue (OR 1.71, 95% CI 1.42-2.08), mortality (OR 1.72, 95% CI 1.44-2.07), and morbidity (OR 1.73, 95% CI 1.60-1.88) vs laparoscopic cases. Open surgery significantly increased the risk of nearly all measured postoperative complications including return to operating room (OR 1.25, 95% CI 1.08-1.45), ventilator use > 48 h (OR 2.43, 95% CI 2.03-2.93), and septic shock (OR 2.34, 95% CI 1.97-2.80). Hospital length of stay was shorter for patients undergoing laparoscopic (10.4 days) vs open (12.3 days) colectomy (p < 0.0001). This study demonstrates the safety and efficacy of the laparoscopic approach for emergent colectomy vs open surgery. Laparoscopy was associated with improved complications rates, mortality, and failure to rescue, indicating that it is a promising option to improve patient outcomes during emergent colectomy.
每年有数千名美国人接受紧急结肠切除术,这带来了显著的发病率和死亡率。尽管腹腔镜技术在择期手术中得到了广泛应用,但在紧急结肠切除术中,其对救援失败的影响尚未在人群水平上进行研究。本研究旨在比较腹腔镜与开腹结肠切除术在紧急情况下的救援失败率。这是一项回顾性队列研究,纳入了美国外科医师学会国家外科质量改进计划数据库中的患者。选择了 2005 年至 2018 年期间接受紧急结肠切除术的成年患者,并使用当前程序术语(Current Procedural Terminology,CPT)代码将其分为腹腔镜或开腹手术组。基于人口统计学和合并症数据进行倾向匹配。主要结局是救援失败、死亡率、总发病率、单个并发症和住院时间。匹配后,共纳入 11484 例患者进行分析,其中 3829 例为腹腔镜手术。总体而言,开腹手术与救援失败(OR 1.71,95%CI 1.42-2.08)、死亡率(OR 1.72,95%CI 1.44-2.07)和发病率(OR 1.73,95%CI 1.60-1.88)的相关性更高。与腹腔镜手术相比,开腹手术显著增加了几乎所有术后并发症的风险,包括重返手术室(OR 1.25,95%CI 1.08-1.45)、呼吸机使用时间超过 48 小时(OR 2.43,95%CI 2.03-2.93)和感染性休克(OR 2.34,95%CI 1.97-2.80)。接受腹腔镜(10.4 天)与开腹(12.3 天)结肠切除术的患者住院时间更短(p<0.0001)。本研究表明,腹腔镜在紧急结肠切除术中是一种安全有效的手术方法,与开腹手术相比,腹腔镜手术可降低并发症发生率、死亡率和救援失败率,表明腹腔镜是一种改善紧急结肠切除术中患者预后的有前途的选择。