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头颈部区域的儿科肿块病变及细针穿刺活检结果。

Pediatric Mass Lesions of the Head and Neck Region and Fine-Needle Aspiration Biopsy Results.

作者信息

Eşki Erkan, Akdoğan Volkan, Türkoğlu Seda Babakurban, Sökmen Muhammed Furkan, Çaylaklı Fatma, Özer Cem, Canpolat Emine Tuba, Yılmaz İsmail

机构信息

Department of Otorhinolaryngology, Başkent University School of Medicine, Ankara, Turkey.

Department of Pathology, Başkent University School of Medicine, Ankara, Turkey.

出版信息

Turk Arch Otorhinolaryngol. 2016 Mar;54(1):29-34. doi: 10.5152/tao.2016.1371. Epub 2016 Mar 1.

Abstract

OBJECTIVE

  1. To provide a classification of pediatric mass of the head and neck region and evaluate their frequency. 2. To examine the findings of fine-needle aspiration biopsy (FNAB) in pediatric patients along with its contribution to diagnosis.

METHODS

Totally, 233 pediatric patients (125 boys and 108 girls) operated at Başkent University for head and neck mass were included. Clinical, radiological, and histopathological data were retrieved from medical records.

RESULTS

The mean age was 119±65 months, and the mean duration of follow-up was 75±49 months. Localization of the masses was as follows: 208 (89%) in the neck, 21 (9%) in the oral cavity, 2 (1%) in the neck and nasopharynx, and two (1%) in the larynx. The most common surgical procedure was open excisional biopsy (n=105, 45%) followed by cystic mass excision (n=72, 31%) and salivary gland excision (n=33, 14%). Based on histopathological findings, benign cystic lesions were the most common disease group (n=77, 33.1%), whereas reactive lymphadenopathy was the most common condition (n=36, 15%) when a single disease was considered. Infectious/inflammatory diseases, malignancies, and benign salivary gland diseases were present in 49 (21%), 24 (10.3%), and 22 (9.4%) patients, respectively. FNAB was performed in 29.8% of the patients with an accuracy of 90.3% (95% CI, 80.1-96.4).

CONCLUSION

The differential diagnosis of head and neck masses during childhood includes a wide spectrum with the different conditions being benign cystic diseases of congenital origin and reactive lymphadenopathies. Owing to its high predictive value, FNAB represents a rapid and reliable method that can be commonly used in both adult and pediatric patients.

摘要

目的

  1. 对儿童头颈部肿块进行分类并评估其发生率。2. 研究儿童患者细针穿刺活检(FNAB)的结果及其对诊断的贡献。

方法

共纳入233例在巴斯肯特大学接受头颈部肿块手术的儿童患者(125例男孩和108例女孩)。从病历中获取临床、放射学和组织病理学数据。

结果

平均年龄为119±65个月,平均随访时间为75±49个月。肿块的定位如下:颈部208例(89%),口腔21例(9%),颈部和鼻咽部2例(1%),喉部2例(1%)。最常见的手术方式是开放性切除活检(n = 105,45%),其次是囊性肿块切除(n = 72,31%)和唾液腺切除(n = 33,14%)。根据组织病理学结果,良性囊性病变是最常见的疾病组(n = 77,33.1%),而当考虑单一疾病时,反应性淋巴结病是最常见的情况(n = 36,15%)。感染/炎症性疾病、恶性肿瘤和良性唾液腺疾病分别存在于49例(21%)、24例(10.3%)和22例(9.4%)患者中。29.8%的患者进行了FNAB,准确率为90.3%(95%CI,80.1 - 96.4)。

结论

儿童期头颈部肿块的鉴别诊断包括广泛的范围,不同情况为先天性良性囊性疾病和反应性淋巴结病。由于其高预测价值,FNAB是一种快速可靠的方法,可普遍应用于成人和儿童患者。

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