细针穿刺活检在非甲状腺头颈部病变中的诊断价值：对866份穿刺样本的回顾性研究
Diagnostic value of fine needle aspiration biopsy in non-thyroidal head and neck lesions: a retrospective study of 866 aspiration materials.
作者信息
Göret Ceren Canbey, Göret Nuri Emrah, Özdemir Zeynep Tuğba, Özkan Esra Akyüz, Doğan Meryem, Yanık Serdar, Gümrükçü Gülistan, Aker Figen Vardar
机构信息
Department of Pathology, Haydarpasa Numune Training and Research Hospital Istanbul, Turkey.
Department of General Surgery, Kartal Dr. Lutfi Kirdar Education and Research Hospital Istanbul, Turkey.
出版信息
Int J Clin Exp Pathol. 2015 Aug 1;8(8):8709-16. eCollection 2015.
AIM
We aimed to investigate the diagnostic value of fine needle aspiration biopsy (FNAB) and compared our FNAB results of non-thyroidal head and neck lesions with excisional biopsy results.
MATERIALS AND METHODS
A total of 866 aspiration material taken from different parts of head and neck region out of thyroid were evaluated at Haydarpasa Numune Training and Research Hospital Pathology Laboratory, between January 2002 and May 2013 and 248 of which has histopathologic response were included in the study. Patients depending on origin of the masses were divided into three categories as; salivary gland, lymph nodes and soft tissue/cystic lesions. The sensitivity, specificity, diagnostic accuracy values of fine needle aspiration biopsies have been investigated for all the series and individually for each category.
FINDINGS
Diagnostic sensitivity, specificity, accuracy, positive predictive value and negative predictive values of non-thyroidal head and neck masses were respectively; For all of the series; 94.6%, 97.9%, 96.7%, 95.9%, 97.2%, Salivary gland: 88.9%, 100%, 98.8%, 100%, 98.7%, Lymph nodes: 94.7%, 89.3%, 92.9%, 94.7%, 89.2%, Soft tissue/cystic lesions: 100%, 100%, 100%, 100%, 100%. For all of the series; there were 4 false negative (FN) cases; and 3 false positive (FP) cases.
CONCLUSION
FNAB in the diagnosis of head and neck masses; it is an easy, cheap and usefull procedure.
目的
我们旨在研究细针穿刺活检（FNAB）的诊断价值，并将我们对非甲状腺头颈部病变的FNAB结果与切除活检结果进行比较。
材料与方法
2002年1月至2013年5月期间，在海达尔帕萨努穆内培训和研究医院病理实验室对从甲状腺以外的头颈部不同部位采集的866份穿刺材料进行了评估，其中248份有组织病理学反应的被纳入研究。根据肿块的起源，患者被分为三类：唾液腺、淋巴结和软组织/囊性病变。对所有系列以及每个类别分别研究了细针穿刺活检的敏感性、特异性、诊断准确性值。
结果
非甲状腺头颈部肿块的诊断敏感性、特异性、准确性、阳性预测值和阴性预测值分别为：对于所有系列；94.6%、97.9%、96.7%、95.9%、97.2%，唾液腺：88.9%、100%、98.8%、100%、98.7%，淋巴结：94.7%、89.3%、92.9%、94.7%、89.2%，软组织/囊性病变：100%、100%、100%、100%、100%。对于所有系列；有4例假阴性（FN）病例；和3例假阳性（FP）病例。
结论
FNAB在头颈部肿块的诊断中；是一种简单、廉价且有用的方法。
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