Amedee R G, Dhurandhar N R
Department of Otolaryngology-Head and Neck Surgery, Tulane University Health Sciences Center, New Orleans, Louisiana 70112-2699, USA.
Laryngoscope. 2001 Sep;111(9):1551-7. doi: 10.1097/00005537-200109000-00011.
Fine-needle aspiration biopsy (FNAB) is a technique in which a fine needle is introduced into a mass, cellular material is aspirated, and a cytological diagnosis is rendered. It separates reactive and inflammatory processes that do not require surgical intervention from neoplasia and benign from malignant tumors. FNAB lends itself to the diagnosis of palpable head and neck masses, in particular, those that persist following antibiotic treatment.
STUDY DESIGN/METHODS: This clinical state-of-the-art review article is intended to provide an overview of the clinical use of FNAB in the management of head and neck masses. Relevant case histories are used to illustrate this point.
Fine-needle aspiration biopsy has a high overall diagnostic accuracy of 95% for all head and neck masses, 95% for benign lesions, and 87% for malignant ones.
There are virtually no contraindications, and complications are minimal. Advantages of FNAB are that it is safe and simple, it can be performed as an outpatient procedure, and it is well tolerated by patients. In the present managed care environment, it also proves cost-effective. The diagnosis is readily known to the clinician, and appropriate treatment modalities can be discussed with the patient. It is recommended as a first line of investigation in palpable head and neck masses.
细针穿刺活检（FNAB）是一种将细针插入肿块、吸取细胞材料并进行细胞学诊断的技术。它能区分不需要手术干预的反应性和炎症性病变与肿瘤，以及良性肿瘤与恶性肿瘤。FNAB尤其适用于诊断可触及的头颈部肿块，特别是那些在抗生素治疗后仍持续存在的肿块。
研究设计/方法：这篇临床最新进展综述文章旨在概述FNAB在头颈部肿块管理中的临床应用。通过相关病例史来说明这一点。
细针穿刺活检对所有头颈部肿块的总体诊断准确率较高，为95%，对良性病变的诊断准确率为95%，对恶性病变的诊断准确率为87%。
几乎没有禁忌证，并发症也很少。FNAB的优点是安全、简单，可以作为门诊手术进行，患者耐受性良好。在当前的管理式医疗环境中，它也被证明具有成本效益。临床医生可以很快得知诊断结果，并能与患者讨论合适的治疗方式。建议将其作为可触及头颈部肿块的一线检查方法。
