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生殖责任的重新分配:论产前干预中“环境”的表观遗传学

The Redistribution of Reproductive Responsibility: On the Epigenetics of "Environment" in Prenatal Interventions.

作者信息

Valdez Natali

机构信息

Center for the Study of Women's Gender and Sexuality, Rice University, Department of Women's and Gender Studies, Wellesley College.

出版信息

Med Anthropol Q. 2018 Sep;32(3):425-442. doi: 10.1111/maq.12424. Epub 2018 Feb 1.

Abstract

The rapidly shifting field of epigenetics has expanded scientific understanding of how environmental conditions affect gene expression and development. This article focuses on two ongoing clinical trials-one in the United States and one in the United Kingdom-that have used epigenetics as the conceptual basis for testing the relationship between nutrition and obesity during pregnancy. Drawing on ethnographic research, I highlight the different ways that clinical scientists interpret epigenetics to target particular domains of the environment for prenatal intervention. Here I examine three environmental domains: the pregnant body, the home, and everyday experiences. In so doing, I show how different scientific approaches to epigenetics multiply concepts of "the environment," while also individualizing responsibility onto pregnant bodies. Ultimately, I argue that how the environment is conceptualized in epigenetics is both a scientific and a political project that opens up questions of reproductive responsibility.

摘要

迅速发展的表观遗传学领域拓展了科学界对于环境条件如何影响基因表达和发育的理解。本文聚焦于两项正在进行的临床试验——一项在美国,一项在英国——它们将表观遗传学作为概念基础,来测试孕期营养与肥胖之间的关系。借助人种志研究,我强调了临床科学家解读表观遗传学的不同方式,以便针对产前干预确定特定的环境领域。在此,我审视三个环境领域:孕妇的身体、家庭和日常经历。通过这样做,我展示了表观遗传学的不同科学方法如何使“环境”概念多样化,同时也将责任个体化到孕妇身体上。最终,我认为表观遗传学中环境的概念化方式既是一个科学项目,也是一个政治项目,它引发了生殖责任的问题。

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