Okayama Sachiyo, Yoshimatsu Kazuhiko, Yokomizo Hajime, Yano Yuki, Yamada Yasufumi, Satake Masaya, Sakuma Akiko, Matsumoto Atsuo, Fujimoto Takashi, Usui Takefumi, Yamaguchi Kentaro, Shiozawa Shunichi, Shimakawa Takeshi, Katsube Takao, Naritaka Yoshihiko
Dept. of Surgery, Tokyo Women's Medical University Medical Center East.
Gan To Kagaku Ryoho. 2017 Nov;44(12):1197-1199.
We report a case of an advanced rectal cancer recurrence that responded completely to chemo-radiotherapy. The patient was an 80-year-old woman. Low anterior resection with D2(prxD3)lymph node dissection was performed. Sixteen months after operation, CEA level elevated but no recurrence foci were found in any image tests. Administration of TS-1 was initiated since recurrence was highly suspected. Twenty seven months after operation, PET-CT detected local recurrence in the posterior wall of the vagina. After construction colostomy, chemo-radiotherapy(60 Gy+oral UFT)was performed and CEA level dropped promptly to the normal value. No relapse was pointed out in CT scans or MRI tests. There were not any signs of recurrence through 112 months after chemo-radiotherapy.
我们报告了一例晚期直肠癌复发患者,其对放化疗完全缓解。患者为一名80岁女性。行低位前切除术及D2(prxD3)淋巴结清扫术。术后16个月,癌胚抗原(CEA)水平升高,但任何影像学检查均未发现复发灶。由于高度怀疑复发,开始给予替吉奥(TS-1)治疗。术后27个月,正电子发射断层显像-X线计算机体层摄影术(PET-CT)检测到阴道后壁局部复发。行结肠造口术后,进行了放化疗(60 Gy+口服优福定),CEA水平迅速降至正常。计算机断层扫描(CT)或磁共振成像(MRI)检查未提示复发。放化疗后112个月未出现任何复发迹象。