Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.
作者信息
Solís Eric J, Pandey Jai P, Zheng Xu, Jin Dexter X, Gupta Piyush B, Airoldi Edoardo M, Pincus David, Denic Vladimir
出版信息
Mol Cell. 2018 Feb 1;69(3):534. doi: 10.1016/j.molcel.2018.01.021.
Abstract
摘要
相似文献
1
Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis.确定酵母热休克转录因子1的基本功能揭示了维持真核生物蛋白质稳态的紧凑转录程序。
Mol Cell. 2018 Feb 1;69(3):534. doi: 10.1016/j.molcel.2018.01.021.
2
Emerging roles of HSF1 in cancer: Cellular and molecular episodes.HSF1 在癌症中的新兴作用：细胞和分子事件。
Biochim Biophys Acta Rev Cancer. 2020 Aug;1874(1):188390. doi: 10.1016/j.bbcan.2020.188390. Epub 2020 Jul 9.
3
HSF1 Activation Can Restrict HIV Replication.热休克因子1（HSF1）的激活可限制HIV复制。
ACS Infect Dis. 2020 Jul 10;6(7):1659-1666. doi: 10.1021/acsinfecdis.0c00166. Epub 2020 Jun 10.
4
Regulation of the Hsf1-dependent transcriptome via conserved bipartite contacts with Hsp70 promotes survival in yeast.通过与 Hsp70 形成保守的二聚体接触来调控 Hsf1 依赖性转录组可促进酵母的存活。
J Biol Chem. 2019 Aug 9;294(32):12191-12202. doi: 10.1074/jbc.RA119.008822. Epub 2019 Jun 25.
5
Hsf1 Phosphorylation Generates Cell-to-Cell Variation in Hsp90 Levels and Promotes Phenotypic Plasticity.Hsf1 磷酸化导致 Hsp90 水平在细胞间的变化，并促进表型可塑性。
Cell Rep. 2018 Mar 20;22(12):3099-3106. doi: 10.1016/j.celrep.2018.02.083.
6
HSF1Base: A Comprehensive Database of HSF1 (Heat Shock Factor 1) Target Genes.HSF1Base：一个全面的 HSF1（热休克因子 1）靶基因数据库。
Int J Mol Sci. 2019 Nov 19;20(22):5815. doi: 10.3390/ijms20225815.
7
Heat shock factor 1 (HSF1)-targeted anticancer therapeutics: overview of current preclinical progress.热休克因子 1（HSF1）靶向抗癌治疗药物：当前临床前进展概述。
Expert Opin Ther Targets. 2019 May;23(5):369-377. doi: 10.1080/14728222.2019.1602119. Epub 2019 Apr 7.
8
Cytoplasmic protein misfolding titrates Hsp70 to activate nuclear Hsf1.细胞质蛋白错误折叠使 Hsp70 达到滴定浓度，从而激活核 Hsf1。
Elife. 2019 Sep 25;8:e47791. doi: 10.7554/eLife.47791.
9
A Novel mouse model of enhanced proteostasis: Full-length human heat shock factor 1 transgenic mice.一种增强蛋白质稳定性的新型小鼠模型：全长人热休克因子 1 转基因小鼠。
Biochem Biophys Res Commun. 2010 Nov 5;402(1):59-65. doi: 10.1016/j.bbrc.2010.09.111. Epub 2010 Oct 13.
10
The heat-shock, or HSF1-mediated proteotoxic stress, response in cancer: from proteomic stability to oncogenesis.热休克蛋白，或 HSF1 介导的蛋白毒性应激反应在癌症中的作用：从蛋白质组稳定性到致癌作用。
Philos Trans R Soc Lond B Biol Sci. 2018 Jan 19;373(1738). doi: 10.1098/rstb.2016.0525.
引用本文的文献
1
An experimental target-based platform in yeast for screening Plasmodium vivax deoxyhypusine synthase inhibitors.一种基于酵母的实验性靶向平台，用于筛选间日疟原虫脱氧hypusine合酶抑制剂。
PLoS Negl Trop Dis. 2024 Dec 2;18(12):e0012690. doi: 10.1371/journal.pntd.0012690. eCollection 2024 Dec.
2
Overexpression profiling reveals cellular requirements in the context of genetic backgrounds and environments.过表达谱分析揭示了遗传背景和环境背景下细胞的需求。
PLoS Genet. 2023 Apr 28;19(4):e1010732. doi: 10.1371/journal.pgen.1010732. eCollection 2023 Apr.
3
Balanced activities of Hsp70 and the ubiquitin proteasome system underlie cellular protein homeostasis.热休克蛋白70（Hsp70）与泛素蛋白酶体系统的平衡活动是细胞蛋白质稳态的基础。
Front Mol Biosci. 2023 Jan 4;9:1106477. doi: 10.3389/fmolb.2022.1106477. eCollection 2022.
4
Massive expression of cysteine-containing proteins causes abnormal elongation of yeast cells by perturbing the proteasome.大量含半胱氨酸的蛋白质的表达通过扰乱蛋白酶体导致酵母细胞的异常伸长。
G3 (Bethesda). 2022 May 30;12(6). doi: 10.1093/g3journal/jkac106.
5
Adaptability of the ubiquitin-proteasome system to proteolytic and folding stressors.泛素-蛋白酶体系统对蛋白水解和折叠胁迫的适应性。
J Cell Biol. 2021 Mar 1;220(3). doi: 10.1083/jcb.201912041.
6
Neuroprotection by Heat Shock Factor-1 (HSF1) and Trimerization-Deficient Mutant Identifies Novel Alterations in Gene Expression.热休克因子-1 (HSF1) 的神经保护作用和三聚体缺陷突变体鉴定了基因表达的新变化。
Sci Rep. 2018 Nov 22;8(1):17255. doi: 10.1038/s41598-018-35610-1.
Zotero 插件