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呼吸道合胞病毒疫苗的研发:世界卫生组织技术路线图和优先产品特征。

Respiratory syncytial virus vaccine research and development: World Health Organization technological roadmap and preferred product characteristics.

机构信息

World Health Organisation, Geneva, Switzerland.

World Health Organisation, Geneva, Switzerland.

出版信息

Vaccine. 2019 Nov 28;37(50):7394-7395. doi: 10.1016/j.vaccine.2017.09.092. Epub 2018 Feb 1.

Abstract

The respiratory syncytial virus causes a considerable respiratory disease burden globally, most markedly in young infants, in low and middle income countries. A diverse product pipeline illustrates the recent intensification of research and development activities for vaccines and monoclonal antibodies against RSV. With the aim to ensure that product development activities are directed to address the public health needs, the World Health Organization has developed a research and development technical roadmap and articulated product characteristics preferences.

摘要

呼吸道合胞病毒(RSV)在全球范围内造成了相当大的呼吸道疾病负担,在中低收入国家,这种负担在婴幼儿中最为显著。多样化的产品管线表明,针对 RSV 的疫苗和单克隆抗体的研发活动最近有所加强。为确保产品开发活动针对解决公共卫生需求,世界卫生组织制定了研发技术路线图,并明确了产品特性偏好。

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