• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

软骨修复:微骨折术与自体骨软骨移植术

Cartilage Restoration: Microfracture and Osteochondral Autograft Transplantation.

作者信息

Redondo Michael L, Beer Adam J, Yanke Adam B

机构信息

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.

出版信息

J Knee Surg. 2018 Mar;31(3):231-238. doi: 10.1055/s-0037-1618592. Epub 2018 Feb 2.

DOI:10.1055/s-0037-1618592
PMID:29396963
Abstract

The treatment of patellofemoral cartilage defects presents several distinct challenges when compared with cartilage restoration techniques used for other compartments of the knee due to the unique anatomy and distribution of forces. The etiologies of patellofemoral articular cartilage lesions include acute traumatic instability injuries, such as dislocation and subluxation, osteochondritis dissecans, and chronic degenerative changes. Regardless of the etiology, untreated patellofemoral cartilage lesions can contribute to activity-limiting anterior knee pain. The goal of patellofemoral cartilage restoration procedures is to impart symptomatic relief and improve quality of life by repairing the articular cartilage surface and any comorbid malalignment or maltracking.Microfracture and osteochondral autograft transplantation (OAT) are two cartilage restoration procedures to consider when treating full-thickness patellofemoral chondral defects. Considered by some experts to be the gold standard therapy, microfracture is one of the most common procedures used for cartilage restoration. The technique involves the perforation of the subchondral bone plate for the release of marrow elements, filling the defect with a fibrocartilage clot repair. Though less commonly used, OAT allows defect replacement with native hyaline cartilage via autologous transplantation from a non-weight bearing area. The purpose of this article is to discuss the indication, technical considerations, and outcomes of microfracture and OAT when used for treating chondral lesions of the patellofemoral joint.

摘要

与用于膝关节其他部位的软骨修复技术相比,由于独特的解剖结构和力的分布,髌股关节软骨缺损的治疗存在几个明显的挑战。髌股关节软骨损伤的病因包括急性创伤性不稳定损伤,如脱位和半脱位、剥脱性骨软骨炎以及慢性退行性改变。无论病因如何,未经治疗的髌股关节软骨损伤都会导致限制活动的膝前疼痛。髌股关节软骨修复手术的目标是通过修复关节软骨表面以及任何合并的排列不齐或轨迹不良来缓解症状并提高生活质量。微骨折和自体骨软骨移植(OAT)是治疗全层髌股关节软骨缺损时可考虑的两种软骨修复手术。微骨折被一些专家视为金标准疗法,是最常用于软骨修复的手术之一。该技术包括穿透软骨下骨板以释放骨髓成分,用纤维软骨凝块修复填充缺损。虽然OAT使用较少,但它可以通过从非负重区域进行自体移植,用天然透明软骨替代缺损。本文的目的是讨论微骨折和OAT用于治疗髌股关节软骨损伤时的适应症、技术要点和结果。

相似文献

1
Cartilage Restoration: Microfracture and Osteochondral Autograft Transplantation.软骨修复:微骨折术与自体骨软骨移植术
J Knee Surg. 2018 Mar;31(3):231-238. doi: 10.1055/s-0037-1618592. Epub 2018 Feb 2.
2
CaReS (MACT) versus microfracture in treating symptomatic patellofemoral cartilage defects: a retrospective matched-pair analysis.比较CaReS(微骨折术)与微骨折术治疗有症状的髌股关节软骨缺损:一项回顾性配对分析。
J Orthop Sci. 2013 Jan;18(1):38-44. doi: 10.1007/s00776-012-0305-x. Epub 2012 Sep 22.
3
Cartilage Restoration Techniques for the Patellofemoral Joint.髌股关节软骨修复技术
J Am Acad Orthop Surg. 2017 May;25(5):321-329. doi: 10.5435/JAAOS-D-15-00447.
4
Considerations in Evaluating Treatment Options for Patellofemoral Cartilage Pathology.评估髌股关节软骨病变治疗方案时的注意事项。
Sports Med Arthrosc Rev. 2016 Jun;24(2):92-7. doi: 10.1097/JSA.0000000000000104.
5
Activity levels are higher after osteochondral autograft transfer mosaicplasty than after microfracture for articular cartilage defects of the knee: a retrospective comparative study.骨软骨马赛克移植成形术治疗膝关节软骨缺损后活动水平高于微骨折术:一项回顾性对比研究。
J Bone Joint Surg Am. 2012 Jun 6;94(11):971-8. doi: 10.2106/JBJS.K.00815.
6
Changing trends in the use of cartilage restoration techniques for the patellofemoral joint: a systematic review.髌股关节软骨修复技术应用变化趋势的系统评价。
Knee Surg Sports Traumatol Arthrosc. 2019 Mar;27(3):854-867. doi: 10.1007/s00167-018-5139-4. Epub 2018 Sep 19.
7
A prospective, randomized clinical study of osteochondral autologous transplantation versus microfracture for the treatment of osteochondritis dissecans in the knee joint in children.一项关于自体骨软骨移植与微骨折术治疗儿童膝关节剥脱性骨软骨炎的前瞻性随机临床研究。
J Pediatr Orthop. 2009 Oct-Nov;29(7):741-8. doi: 10.1097/BPO.0b013e3181b8f6c7.
8
Knee Articular Cartilage Repair and Restoration Techniques: A Review of the Literature.膝关节软骨修复与重建技术:文献综述
Sports Health. 2016 Mar-Apr;8(2):153-60. doi: 10.1177/1941738115611350. Epub 2015 Oct 12.
9
Microfracture and Microfracture Plus.微骨折术及微骨折术联合其他治疗
Clin Sports Med. 2017 Jul;36(3):501-507. doi: 10.1016/j.csm.2017.02.012. Epub 2017 Apr 15.
10
Can osteochondral grafting be augmented with microfracture in an extended-size lesion of articular cartilage?在关节软骨大面积损伤中,采用微骨折技术辅助骨软骨移植是否可行?
Am J Sports Med. 2010 Jul;38(7):1316-23. doi: 10.1177/0363546510363433. Epub 2010 Apr 16.

引用本文的文献

1
An Overview of Approaches and Evaluation Methods for Tissue-Engineered Articular Cartilage Constructs in Animal Models.动物模型中组织工程化关节软骨构建体的方法与评估方法概述
Ann Biomed Eng. 2025 Aug 19. doi: 10.1007/s10439-025-03819-7.
2
Immunomodulatory biomaterials for osteoarthritis: Targeting inflammation and enhancing cartilage regeneration.用于骨关节炎的免疫调节生物材料:靶向炎症并促进软骨再生
Mater Today Bio. 2025 Jul 16;34:102100. doi: 10.1016/j.mtbio.2025.102100. eCollection 2025 Oct.
3
Multifunctional MeHA hydrogel for living materials delivery with enhanced cartilage regeneration.
用于生物材料递送并增强软骨再生的多功能甲基丙烯酸羟乙酯水凝胶。
Front Bioeng Biotechnol. 2025 May 30;13:1545773. doi: 10.3389/fbioe.2025.1545773. eCollection 2025.
4
Tissue Engineered Cartilage Repair Using Small-Incision Implantation of Decalcified Corticocancellous Bone Scaffold.使用小切口植入脱钙皮质松质骨支架进行组织工程软骨修复
Arthrosc Tech. 2024 Dec 10;14(4):103346. doi: 10.1016/j.eats.2024.103346. eCollection 2025 Apr.
5
Patellar MACI With Tibial Tubercle Osteotomy.髌骨关节面软骨损伤修复术联合胫骨结节截骨术
Video J Sports Med. 2022 Jan 11;2(1):26350254211053013. doi: 10.1177/26350254211053013. eCollection 2022 Jan-Feb.
6
[Arthroscopic tissue engineering scaffold repair for cartilage injuries].[关节镜下组织工程支架修复软骨损伤]
Beijing Da Xue Xue Bao Yi Xue Ban. 2025 Apr 18;57(2):384-387. doi: 10.19723/j.issn.1671-167X.2025.02.025.
7
Nanocomposite Hydrogels: A Promising Approach for the Treatment of Degenerative Joint Diseases.纳米复合水凝胶:一种治疗退行性关节疾病的有前景的方法。
Small Sci. 2024 Sep 3;4(11):2400236. doi: 10.1002/smsc.202400236. eCollection 2024 Nov.
8
Targeting the reorganization of F-actin for cell-based implantation cartilage repair therapies.针对基于细胞的植入式软骨修复疗法中F-肌动蛋白的重组。
Differentiation. 2025 May-Jun;143:100847. doi: 10.1016/j.diff.2025.100847. Epub 2025 Mar 1.
9
Advanced progress of adipose-derived stem cells-related biomaterials in maxillofacial regeneration.脂肪来源干细胞相关生物材料在颌面再生中的研究进展
Stem Cell Res Ther. 2025 Mar 5;16(1):110. doi: 10.1186/s13287-025-04191-y.
10
Delayed lubricin injection improves cartilage repair tissue quality in an in vivo rabbit osteochondral defect model.延迟注射润滑素可改善兔体内骨软骨缺损模型中的软骨修复组织质量。
bioRxiv. 2025 Feb 8:2025.02.06.636825. doi: 10.1101/2025.02.06.636825.