JDP2: A novel therapeutic thought in cardiac remodeling.

作者信息

Guo Xin, Hu Shan, Chen Jing, Jiang Hong

机构信息

Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute of Wuhan University, Wuhan 430060, Hubei Province, China.

出版信息

Int J Cardiol. 2018 Apr 15;257:229. doi: 10.1016/j.ijcard.2017.09.210. Epub 2018 Feb 4.

DOI:10.1016/j.ijcard.2017.09.210

PMID:29397205

Abstract

摘要

相似文献

JDP2: A novel therapeutic thought in cardiac remodeling.

Int J Cardiol. 2018 Apr 15;257:229. doi: 10.1016/j.ijcard.2017.09.210. Epub 2018 Feb 4.

JDP2 and ATF3 deficiencies dampen maladaptive cardiac remodeling and preserve cardiac function.JDP2 和 ATF3 缺失可抑制适应性心脏重构并维持心脏功能。

PLoS One. 2019 Feb 28;14(2):e0213081. doi: 10.1371/journal.pone.0213081. eCollection 2019.

JDP2 and ATF3 - bZIP repressors in cardiac remodeling.心脏重塑中的JDP2和ATF3 - bZIP阻遏物

Int J Cardiol. 2018 Apr 15;257:228. doi: 10.1016/j.ijcard.2017.12.099.

Inhibition of AP-1 signaling by JDP2 overexpression protects cardiomyocytes against hypertrophy and apoptosis induction.JDP2 过表达抑制 AP-1 信号转导，保护心肌细胞免受肥大和凋亡诱导。

Cardiovasc Res. 2013 Jul 1;99(1):121-8. doi: 10.1093/cvr/cvt094. Epub 2013 Apr 23.

The transcription factor Jdp2 controls bone homeostasis and antibacterial immunity by regulating osteoclast and neutrophil differentiation.转录因子 Jdp2 通过调节破骨细胞和中性粒细胞分化来控制骨稳态和抗菌免疫。

Immunity. 2012 Dec 14;37(6):1024-36. doi: 10.1016/j.immuni.2012.08.022. Epub 2012 Nov 29.

Differential targeting of the stress mitogen-activated protein kinases to the c-Jun dimerization protein 2.应激丝裂原活化蛋白激酶对c-Jun二聚化蛋白2的差异性靶向作用。

Biochem J. 2002 Dec 15;368(Pt 3):939-45. doi: 10.1042/BJ20021127.

A potential therapeutic approach to cardiac remodeling: JDP2.一种针对心脏重塑的潜在治疗方法：JDP2。

Int J Cardiol. 2018 Mar 1;254:283. doi: 10.1016/j.ijcard.2017.10.083. Epub 2018 Jan 28.

The AP-1 repressor protein, JDP2, potentiates hepatocellular carcinoma in mice.AP-1 抑制蛋白 JDP2 增强了小鼠的肝细胞癌。

Mol Cancer. 2010 Mar 9;9:54. doi: 10.1186/1476-4598-9-54.

IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription.干扰素调节因子2结合蛋白1是一种JDP2泛素连接酶，也是一种依赖于ATF2转录的抑制剂。

FEBS Lett. 2008 Aug 20;582(19):2833-7. doi: 10.1016/j.febslet.2008.07.033. Epub 2008 Jul 29.

The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.心肌细胞与巨噬细胞之间由ATF3介导的心脏适应性不良的相互作用是由IFNγ-CXCL10-CXCR3轴介导的。

Int J Cardiol. 2017 Feb 1;228:394-400. doi: 10.1016/j.ijcard.2016.11.159. Epub 2016 Nov 10.

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