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[甲状腺素对遗传性肌营养不良症骨骼肌的影响]

[Effect of thyroxine on skeletal muscles in hereditary myodystrophia].

作者信息

Khamitov Kh S, Bogdanov E I

出版信息

Biull Eksp Biol Med. 1986 May;101(5):540-3.

PMID:2939889
Abstract

The influence of 3-week L-thyroxin administration on contractility and histochemical composition of skeletal muscles was studied in 129Rj mice of normal and dystrophic genotypes. The rise in speed characteristics of isometric contraction and percentage of type II "fast" fibers was established in both types of animals. Contractile properties in dystrophic animals, receiving L-thyroxin, showed a tendency towards normalization and were comparable to those of normal animals.

摘要

在正常基因型和营养不良基因型的129Rj小鼠中,研究了为期3周的L-甲状腺素给药对骨骼肌收缩性和组织化学组成的影响。在这两种类型的动物中,等长收缩的速度特征和II型“快”纤维的百分比均有所增加。接受L-甲状腺素的营养不良动物的收缩特性呈现出正常化的趋势,并且与正常动物相当。

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