Reichmann H, Pette D
Muscle Nerve. 1984 Feb;7(2):121-6. doi: 10.1002/mus.880070206.
Enzyme activities of energy metabolism were determined in both homogenates and single fibers of immature-normal (IN), adult-normal (AN), and adult-dystrophic (AD) tibialis anterior (TA) muscle of BL6 mice. Mitochondrial enzyme activities were similar in AN and AD, whereas lower activities were found in IN. Creatine kinase, glycogenolytic, and glycolytic enzyme activities were reduced but glucose 6-phosphate dehydrogenase was elevated in AD and IN as compared to AN. IN and AD both showed an increase in the H-subunit of lactate dehydrogenase. Microphotometric measurements of succinate dehydrogenase (SDH) revealed large fiber differences in AN whereas smaller scattering was observed both in IN and AD. Although similarities exist between enzyme and isozyme patterns of anaerobic metabolism in AD and IN, this does not hold for mitochondrial enzymes.
在BL6小鼠的未成熟正常（IN）、成年正常（AN）和成年营养不良（AD）胫前肌（TA）的匀浆和单根纤维中测定了能量代谢的酶活性。AN和AD的线粒体酶活性相似，而IN中的活性较低。与AN相比，AD和IN中的肌酸激酶、糖原分解酶和糖酵解酶活性降低，但葡萄糖6-磷酸脱氢酶升高。IN和AD的乳酸脱氢酶H亚基均增加。琥珀酸脱氢酶（SDH）的显微光度测量显示AN中纤维差异大，而IN和AD中散射较小。尽管AD和IN的无氧代谢酶和同工酶模式存在相似性，但线粒体酶并非如此。
