Department of Dermatology, Tohoku University Graduate School of Medicine, Sendai, Japan.
Department of Pediatrics, Tohoku University Graduate School of Medicine, Sendai, Japan.
J Dermatol. 2018 May;45(5):606-608. doi: 10.1111/1346-8138.14243. Epub 2018 Feb 5.
We report a 9-year-old Japanese female patient with atopic dermatitis associated with idiopathic thrombocytopenic purpura. She demonstrated high serum immunoglobulin (Ig)E and IgE specific to several environmental allergens, but extremely low serum thymus and activation-regulated chemokine (TARC) levels regardless of the disease progression. This case suggests platelets as the main source of serum TARC.
我们报告了一例 9 岁日本女性特应性皮炎伴特发性血小板减少性紫癜患者。她表现出高血清免疫球蛋白(Ig)E 和对多种环境过敏原的 IgE 特异性,但无论疾病进展如何,血清胸腺和激活调节趋化因子(TARC)水平极低。该病例提示血小板是血清 TARC 的主要来源。