Cameron N E, Cotter M A, Harrison J
Exp Neurol. 1986 Jun;92(3):757-61. doi: 10.1016/0014-4886(86)90315-8.
Motor nerve conduction velocity was measured in six branches of the sciatic nerve in streptozotocin-diabetic rats. It was markedly reduced in nerves to the gastrocnemius, soleus, tibialis anterior, and extensor digitorum longus muscles. The branch to the plantaris muscle remained unaffected. In control rats none of these branches showed any evidence of conduction velocity maturation over the 2-month experimental period. Motor nerve conduction velocity to the interosseus muscles of the foot did show a normal maturation effect, which was halted by diabetes. We conclude that large-caliber motor fibers in mature nerves are particularly susceptible to diabetes.
在链脲佐菌素诱导的糖尿病大鼠中，测量了坐骨神经六个分支的运动神经传导速度。腓肠肌、比目鱼肌、胫骨前肌和趾长伸肌的神经传导速度显著降低。至跖肌的分支未受影响。在对照大鼠中，在2个月的实验期内，这些分支均未显示出传导速度成熟的任何迹象。至足部骨间肌的运动神经传导速度确实显示出正常的成熟效应，但糖尿病使其停止。我们得出结论，成熟神经中的大口径运动纤维对糖尿病特别敏感。
