Suppr超能文献

超觉静坐法对退伍军人创伤后应激障碍症状的影响:一项非对照性初步研究。

The Transcendental Meditation Program's Impact on the Symptoms of Post-traumatic Stress Disorder of Veterans: An Uncontrolled Pilot Study.

作者信息

Herron Robert E, Rees Brian

机构信息

Center for Health Systems Analysis, P. O. Box 2045, Fairfield, IA 52556.

Executive Director, TM for Veterans, 1100N. Fourth Street, Fairfield, IA 52556.

出版信息

Mil Med. 2018 Jan 1;183(1-2):e144-e150. doi: 10.1093/milmed/usx059.

Abstract

BACKGROUND

Current treatments for post-traumatic stress disorder (PTSD) are only partially effective. This study evaluated whether an extensively researched stress reduction method, the Transcendental Meditation (TM) technique, can reduce the PTSD symptoms of veterans. Previous research suggested that TM practice can decrease veterans' PTSD symptoms.

METHODS

A one-group pretest-posttest design was used to evaluate the impact of TM practice on reducing PTSD symptoms. A convenience sample of 89 veterans completed PTSD Checklist-Civilian (PCL-5) questionnaires. Among those, 46 scored above 33, the threshold for provisional diagnosis of PTSD, and were included in this evaluation. The PCL-5 measured PTSD symptoms at baseline and 30 and 90 d after intervention. Regularity of TM practice was recorded. Paired sample t-tests were used to assess within-group changes from baseline to post-intervention periods. Analysis of variance was used to compare full-dose (two 20-min TM sessions per day) and half-dose (one 20-min TM session per day) groups.

FINDINGS

After 1 mo of TM practice, all 46 veterans responded; their PCL-5 average decreased from 51.52 in the pre-intervention period to a post-intervention mean of 23.43, a decline of 28.09 points (-54.5%); standard deviation: 14.57; confidence interval: 23.76-32.41; and effect size: -1.93; p < 0.0001. The median PTSD scores declined from 52.5 to 22.5, a decrease of 30 points (-57%), while 40 veterans (87%) had clinically significant declines (>10 points) in PTSD symptoms, and 37 (80%) dropped below the clinical level (<33). At the 90 d posttest, 31 of the 46 responded and three more dropped below the 33 threshold. Intent-to-treat analyses revealed clinically and statistically significant effects. A dose-response effect suggested a causal relationship. The full-dose group exhibited larger mean declines in PTSD symptoms than the half-dose group. Averages of the 46 veterans' responses to 20 PCL-5 questions exhibited significant (p < 0.0001) declines from the pre-intervention period to the 30-d post-intervention assessment.

DISCUSSION

Results indicated that TM practice reduced PTSD symptoms without re-experiencing trauma. Because of the magnitude of these results and dose-response effect, regression to the mean, spontaneous remission of symptoms, and placebo effects are unlikely explanations for the results. Major limitations were absence of random assignment and lack of a control group. Participants chose to start and continue TM practice and to complete PCL-5 questionnaires. Those who self-selected to enter this study may not be representative of all veterans who have PTSD. Those who did not complete follow-up questionnaires at 90 d may or may not have had the same results as those who responded. The design and sampling method affect the generalizability of the results to wider populations. When taking into account these results and all previous research on the TM technique in reducing psychological and physiological stress, the convergence of evidence suggests that TM practice may offer a promising adjunct or alternative method for treating PTSD. Because of the widely recognized need to identify effective new approaches for treating PTSD, randomized research with control groups is warranted to further investigate the effectiveness of TM practice as a treatment for PTSD.

摘要

背景

创伤后应激障碍(PTSD)的现有治疗方法仅部分有效。本研究评估了一种经过广泛研究的减压方法——超觉静坐(TM)技巧,是否能减轻退伍军人的PTSD症状。先前的研究表明,练习TM可减轻退伍军人的PTSD症状。

方法

采用单组前后测设计来评估TM练习对减轻PTSD症状的影响。便利抽样选取了89名退伍军人完成创伤后应激障碍检查表 - 平民版(PCL - 5)问卷。其中,46人的得分高于33分(PTSD临时诊断阈值),被纳入本评估。PCL - 5在基线、干预后30天和90天测量PTSD症状。记录TM练习的规律性。采用配对样本t检验评估组内从基线到干预后时期的变化。方差分析用于比较全剂量组(每天两次20分钟的TM练习)和半剂量组(每天一次20分钟的TM练习)。

结果

TM练习1个月后,所有46名退伍军人都有反应;他们PCL - 5的平均分从干预前期的51.52降至干预后的均值23.43,下降了28.09分(-54.5%);标准差:14.57;置信区间:23.76 - 32.41;效应量:-1.93;p < 0.0001。PTSD得分中位数从52.5降至22.5,下降了30分(-57%),同时40名退伍军人(87%)的PTSD症状有临床显著下降(>10分),37人(80%)降至临床水平以下(<33分)。在90天的后测中,46人中有31人有反应,另外3人降至33分阈值以下。意向性分析显示出临床和统计学上的显著效果。剂量反应效应表明存在因果关系。全剂量组在PTSD症状上的平均下降幅度大于半剂量组。46名退伍军人对20个PCL - 5问题的回答平均值从干预前期到干预后30天评估有显著(p < 0.0001)下降。

讨论

结果表明,TM练习减轻了PTSD症状,且无需再次经历创伤。鉴于这些结果的程度和剂量反应效应,结果不太可能是均值回归、症状自发缓解和安慰剂效应所致。主要局限性是缺乏随机分配和对照组。参与者自行选择开始并持续TM练习以及完成PCL - 5问卷。那些自行选择进入本研究的参与者可能不代表所有患有PTSD的退伍军人。那些在90天未完成后续问卷的人可能与有反应的人有相同或不同的结果。设计和抽样方法影响了结果对更广泛人群的普遍性。考虑到这些结果以及之前所有关于TM技巧减轻心理和生理压力的研究,证据的趋同表明TM练习可能为治疗PTSD提供一种有前景的辅助或替代方法。由于广泛认识到需要确定治疗PTSD的有效新方法,因此有必要进行有对照组的随机研究,以进一步调查TM练习作为PTSD治疗方法的有效性。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验