Rosenthal Joshua Z, Grosswald Sarina, Ross Richard, Rosenthal Norman
Capital Clinical Research Associates, 5515 Security Lane, Suite 525, Rockville, MD 20852, USA.
Mil Med. 2011 Jun;176(6):626-30. doi: 10.7205/milmed-d-10-00254.
We conducted an uncontrolled pilot study to determine whether transcendental meditation (TM) might be helpful in treating veterans from Operation Enduring Freedom or Operation Iraqi Freedom with combat-related posttraumatic stress disorder (PTSD). Five veterans were trained in the technique and followed for 12 weeks. All subjects improved on the primary outcome measure, the Clinician Administered PTSD Scale (mean change score, 31.4; p = 0.02; df = 4). Significant improvements were also observed for 3 secondary outcome measures: Clinician's Global Inventory-Severity (mean change score, 1.60; p < 0.04; df = 4), Quality of Life Enjoyment and Satisfaction Questionnaire (mean change score, -13.00; p < 0.01; df = 4), and the PTSD Checklist-Military Version (mean change score, 24.00; p < 0.02; df = 4). TM may have helped to alleviate symptoms of PTSD and improve quality of life in this small group of veterans. Larger, placebo-controlled studies should be undertaken to further determine the efficacy of TM in this population.
我们开展了一项非对照性的初步研究，以确定超觉静坐（TM）是否有助于治疗来自持久自由行动或伊拉克自由行动的患有与战斗相关创伤后应激障碍（PTSD）的退伍军人。五名退伍军人接受了该技术培训，并随访了12周。所有受试者在主要结局指标——临床医生管理的PTSD量表上均有改善（平均变化得分，31.4；p = 0.02；自由度 = 4）。在3项次要结局指标上也观察到显著改善：临床医生总体印象量表-严重程度（平均变化得分，1.60；p < 0.04；自由度 = 4）、生活享受与满意度问卷（平均变化得分，-13.00；p < 0.01；自由度 = 4）以及PTSD检查表-军事版（平均变化得分，24.00；p < 0.02；自由度 = 4）。超觉静坐可能有助于缓解这一小群退伍军人的PTSD症状并改善生活质量。应开展更大规模的、有安慰剂对照的研究，以进一步确定超觉静坐对该人群的疗效。
