Troup J P, Metzger J M, Fitts R H
J Appl Physiol (1985). 1986 May;60(5):1743-51. doi: 10.1152/jappl.1986.60.5.1743.
The purpose of this study was to determine whether a program of regular sprint exercise training alters the functional properties or protects against the development of fatigue in fast- and slow-twitch rat skeletal muscle. The training program consisted of 6 sprints of 4.5-min duration at 40 m/min and 15% slope with 2.5-min rest intervals, performed 5 days/wk for 6 wk. The exercise program significantly increased (P less than 0.05) citrate synthase activity (mumol X g-1 X min-1) in the predominantly type I soleus (SOL) from 28 +/- 2 to 44 +/- 2; the type IIb superficial region of the vastus lateralis (SVL) from 10 +/- 1 to 16 +/- 1; and the type IIa deep region of the vastus lateralis (DVL) from 34 +/- 2 to 53 +/- 2. Phosphofructokinase activity (mumol X g-1 X min-1) also increased with training in the SOL (17 +/- 1 vs. 23 +/- 1) and the DVL (64 +/- 5 vs. 79 +/- 5). Sprint training reduced (P less than 0.05) the contraction time (CT) (111 +/- 7 vs. 92 +/- 3 ms) and the one-half relaxation time (118 +/- 3 vs. 104 +/- 2 ms) in the slow-twitch soleus. The exercise program also induced a decreased CT in the fast-twitch extensor digitorum longus (EDL), but significance was limited to the P less than 0.1 level. Muscle fatigue was produced by electrical stimulation at 45 trains/min and either 15 trains/min in SOL or 10 trains/min in the EDL and SVL for 1, 5, or 10 min.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究的目的是确定定期短跑运动训练计划是否会改变快肌和慢肌大鼠骨骼肌的功能特性或预防疲劳的发生。训练计划包括以40米/分钟的速度和15%的坡度进行6次4.5分钟的冲刺跑，每次冲刺之间休息2.5分钟，每周进行5天，共6周。该运动计划显著提高了（P<0.05）主要为I型的比目鱼肌（SOL）中的柠檬酸合酶活性（微摩尔×克-1×分钟-1），从28±2提高到44±2；股外侧肌IIb型浅部区域（SVL）从10±1提高到16±1；股外侧肌IIa型深部区域（DVL）从34±2提高到53±2。磷酸果糖激酶活性（微摩尔×克-1×分钟-1）在训练后在比目鱼肌（17±1对23±1）和股外侧肌深部区域（64±5对79±5）也有所增加。短跑训练缩短了（P<0.05）慢肌比目鱼肌的收缩时间（CT）（111±7对92±3毫秒）和半松弛时间（118±3对104±2毫秒）。该运动计划还使快肌趾长伸肌（EDL）的收缩时间缩短，但显著性仅限于P<0.1水平。通过以45次/分钟的频率进行电刺激产生肌肉疲劳，在比目鱼肌中以15次/分钟、在趾长伸肌和股外侧肌浅部区域以10次/分钟进行电刺激，持续1、5或10分钟。（摘要截断于250字）
