Parmar Arpit, Verma Rohit
Department of Psychiatry and NDDTC, All India Institute of Medical Sciences, New Delhi, India.
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India.
Indian J Psychol Med. 2018 Jan-Feb;40(1):86-88. doi: 10.4103/IJPSYM.IJPSYM_1_17.
Obsessive-compulsive disorder (OCD) is a common neuropsychiatric disorder, with predominant involvement of cortico-striato-thalamo-cortico circuitry. Although late-onset cases (>35 years) usually show an association with various neurological disorders involving basal ganglia and thalamus, it is not the case with the young-onset patients. There have been no reports of OCD comorbid with dysferlinopathy which is usually considered as a disease involving only muscles. However, recently, studies suggest involvement of brain in this disease. Here, we report a case of dysferlinopathy comorbid with OCD and discuss the related literature.
强迫症(OCD)是一种常见的神经精神疾病,主要累及皮质-纹状体-丘脑-皮质环路。虽然晚发型病例(>35岁)通常与涉及基底神经节和丘脑的各种神经系统疾病有关,但早发型患者并非如此。目前尚无强迫症与dysferlinopathy共病的报道,后者通常被认为是一种仅累及肌肉的疾病。然而,最近的研究表明大脑也参与了这种疾病。在此,我们报告一例dysferlinopathy合并强迫症的病例并讨论相关文献。