头皮活检水平及垂直切片在各种原发性脱发形式中的应用价值。
Utility of horizontal and vertical sections of scalp biopsies in various forms of primary alopecias.
作者信息
Palo Seetu, Biligi Dayananda S
机构信息
Department of Pathology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.
Department of Pathology, Bangalore Medical College and Research Institute, Bengaluru, Karnataka, India.
出版信息
J Lab Physicians. 2018 Jan-Mar;10(1):95-100. doi: 10.4103/JLP.JLP_4_17.
BACKGROUND
This study was performed to demonstrate the usefulness of horizontal and vertical sections of scalp biopsies in diagnosing various forms of primary alopecias and to highlight the importance of error-free grossing.
MATERIALS AND METHODS
A retrospective analytical review of 228 scalp biopsies was done, noting down the diagnostic histopathological features evident in horizontal and vertical sections of each cases. The idealness of the sections, especially horizontal section, was also analyzed.
RESULTS
Out of the 228 cases, 44 scalp biopsies were classified histologically as cicatricial alopecias and the remaining 162 as noncicatricial alopecia. 22 cases were inconclusive owing to erroneous grossing. We found horizontal sections to be more useful in cases of noncicatricial alopecias, whereas vertical sections proved superior in cicatricial alopecias.
CONCLUSION
Combining both horizontally and vertically sectioned scalp biopsies maximizes the diagnostic yield. When a single biopsy is submitted, the choice between horizontal and vertical section should depend on clinical diagnosis/suspicion.
背景
本研究旨在证明头皮活检的水平切片和垂直切片在诊断各种原发性脱发中的实用性，并强调无误取材的重要性。
材料与方法
对228例头皮活检进行回顾性分析，记录每例水平切片和垂直切片中明显的诊断性组织病理学特征。还分析了切片的理想程度，尤其是水平切片。
结果
在228例病例中，44例头皮活检组织学分类为瘢痕性脱发，其余162例为非瘢痕性脱发。22例因取材错误而诊断不明确。我们发现水平切片在非瘢痕性脱发病例中更有用，而垂直切片在瘢痕性脱发中表现更优。
结论
结合头皮活检的水平切片和垂直切片可使诊断率最大化。当提交单个活检时，水平切片和垂直切片的选择应取决于临床诊断/怀疑。
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