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表现为肺部肿块伴左心房受累的转移性平滑肌肉瘤:病例报告及麻醉处理

Metastatic leiomyosarcoma presenting as a lung mass with left atrial extension: case report and anesthetic management.

作者信息

Qu Yinyin, Zheng Qing, Ni Cheng, Cui Zhongqi, Guo Xiangyang

机构信息

Department of Anesthesiology.

Department of Cardiac Surgery, Peking University Third Hospital, Beijing, People's Republic of China.

出版信息

Ther Clin Risk Manag. 2018 Jan 19;14:141-147. doi: 10.2147/TCRM.S153484. eCollection 2018.

Abstract

INTRODUCTION

Lung metastasis of leiomyosarcoma that protrudes into the left atrium is an extremely rare condition. Severe complications may occur that prominently increase the mortality during the perioperative period. Currently, the anesthetic management reports are limited and there is no generally acknowledged algorithm available.

CASE PRESENTATION

A 67-year-old man presented with cough and dyspnea for 10 days. Workup revealed bilateral pulmonary effusion. Transthoracic echocardiography showed a large mass in the left atrium. Urgent surgical resection under cardiopulmonary bypass was performed. We focused on oxygenation improvement and cardiac function management by applying protective ventilation with low positive end expiratory pressure, low dose inotropic agents, and other methods to maintain stable homeostasis. Results of biopsy established a diagnosis of metastatic leiomyosarcoma.

CONCLUSION

We reported a case of metastatic leiomyosarcoma presenting as a lung mass with left atrial extension and anesthetic management during surgical resection. Treating acute heart failure and refractory hypoxemia was the key focus perioperatively.

摘要

引言

平滑肌肉瘤肺转移并突入左心房是一种极为罕见的情况。可能会出现严重并发症,显著增加围手术期死亡率。目前,麻醉管理报告有限,且尚无普遍认可的算法。

病例介绍

一名67岁男性因咳嗽和呼吸困难10天就诊。检查发现双侧胸腔积液。经胸超声心动图显示左心房有一个大肿块。在体外循环下进行了紧急手术切除。我们通过应用低呼气末正压的保护性通气、低剂量的强心药物及其他方法来改善氧合和管理心功能,以维持稳定的内环境稳态。活检结果确诊为转移性平滑肌肉瘤。

结论

我们报告了一例以肺肿块伴左心房受累表现的转移性平滑肌肉瘤病例及手术切除期间的麻醉管理。围手术期治疗急性心力衰竭和难治性低氧血症是关键重点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/892c/5783153/416a401d42f2/tcrm-14-141Fig1.jpg

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