Ochi Harumi, Tan Lixian Chris, Oon Hazel H
Department of Dermatology, National Skin Centre, Singapore.
Clin Cosmet Investig Dermatol. 2018 Jan 18;11:37-39. doi: 10.2147/CCID.S136730. eCollection 2018.
Hidradenitis suppurativa (HS) is a chronic inflammatory disease of follicular occlusion characterized by abscesses, draining sinuses, and scarring. The efficacy and tolerability of combination treatment with oral clindamycin and rifampicin have previously been assessed in 4 studies including groups of Caucasian patients. Overall results are promising with reported improvement rates between 71.4% and 85.7%. In this study, we propose that combination therapy is safe and efficacious in the treatment of HS, not only among Caucasians, but also in a group of Asian patients in Singapore.
化脓性汗腺炎（HS）是一种毛囊闭塞的慢性炎症性疾病，其特征为脓肿、引流窦道和瘢痕形成。口服克林霉素和利福平联合治疗的疗效和耐受性此前已在4项研究中进行了评估，这些研究纳入了白种人患者组。总体结果很有前景，报告的改善率在71.4%至85.7%之间。在本研究中，我们提出联合治疗在HS的治疗中是安全有效的，不仅对白种人有效，对新加坡的一组亚洲患者也有效。
