非典型角膜地形图患者的准分子激光原位角膜磨镶术治疗效果

Outcomes of photorefractive keratectomy in patients with atypical topography.

作者信息

Movahedan Hossein, Namvar Ehsan, Farvardin Mohsen

机构信息

M.D., Associate Professor of Ophthalmology, Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

M.D., Resident of Ophthalmology, Ophtalmology Department, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Electron Physician. 2017 Nov 25;9(11):5684-5688. doi: 10.19082/5684. eCollection 2017 Nov.

DOI:10.19082/5684

PMID:29403606

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5783115/

Abstract

BACKGROUND

Photorefractive keratectomy (PRK) is at risk of serious complications such as corneal ectasia, which can reduce corrected distance visual acuity. The rate of complications of PRK is higher in patients with atypical topography.

OBJECTIVE

To determine the outcomes of photorefractive keratectomy in patients with atypical topography.

METHODS

This cross-sectional study was done in 2015 in Shiraz in Iran. We included 85 eyes in this study. The samples were selected using a simple random sampling method. All patients were under evaluation for uncorrected distance visual acuity, corrected distance visual acuity, manifest refraction, corneal topography, central corneal thickness using pentacam, slit-lamp microscopy, and detailed fondus evaluation. The postoperative examination was done 1-7 years after surgery. Data were analyzed using IBM SPSS 21.0 version. To analyze the data, descriptive statistics (frequency, percentage, mean, and standard deviation), chi-square, and independent samples t-test were used.

RESULTS

We studied 85 eyes. Among the patients, 23 (27.1%) were male and 62 (72.9%) were female. Mean age of the participants was 28.25±5.55 years. Mean postoperative refraction was - 0.37±0.55 diopters. Keratoconus or corneal ectasia was not reported in any patient in this study. There was no statistically significant difference between SI index before and after operation (p=0.736). Mean preoperative refraction was -3.84 ± 1.46 diopters in males and -4.20±1.96 diopters in females; thus there was not statistically significant difference (p = 0.435).

CONCLUSION

PRK is a safe and efficient photorefractive surgery and is associated with low complication rate in patients with atypical topography.

摘要

背景

准分子激光角膜切削术（PRK）存在诸如角膜扩张等严重并发症的风险，这可能会降低矫正远视力。非典型角膜地形图患者的PRK并发症发生率更高。

目的

确定非典型角膜地形图患者行准分子激光角膜切削术的效果。

方法

这项横断面研究于2015年在伊朗设拉子进行。本研究纳入了85只眼。样本采用简单随机抽样方法选取。所有患者均接受未矫正远视力、矫正远视力、显验光、角膜地形图、使用Pentacam测量中央角膜厚度、裂隙灯显微镜检查以及详细的眼底评估。术后检查在手术后1至7年进行。数据使用IBM SPSS 21.0版本进行分析。为分析数据，使用了描述性统计（频率、百分比、均值和标准差）、卡方检验和独立样本t检验。

结果

我们研究了85只眼。患者中，男性23例（27.1%），女性62例（72.9%）。参与者的平均年龄为28.25±5.55岁。术后平均屈光度为-0.37±0.55屈光度。本研究中未报告任何患者发生圆锥角膜或角膜扩张。手术前后的SI指数之间无统计学显著差异（p=0.736）。男性术前平均屈光度为-3.84±1.46屈光度，女性为-4.20±1.96屈光度；因此无统计学显著差异（p = 0.435）。