Yildirim Yusuf, Olcucu Onur, Alagoz Nese, Agca Alper, Karakucuk Yalcin, Demirok Ahmet
Beyoglu Eye Training and Research Hospital, Bereketzade Mah. Bereketzade Cami Sok. No: 2, 34420, Beyoglu, Istanbul, Turkey.
Kirklareli Government Hospital, Kirklareli, Turkey.
Int Ophthalmol. 2018 Apr;38(2):627-633. doi: 10.1007/s10792-017-0501-y. Epub 2017 Mar 27.
To compare postoperative visual outcomes and higher-order aberrations (HOAs) following transepithelial photorefractive keratectomy (t-PRK) and mechanical photorefractive keratectomy (m-PRK).
The medical records of patients who underwent photorefractive keratectomy (PRK) were retrospectively evaluated. Forty-five patients were treated with m-PRK, and 45 were treated with t-PRK. Visual acuity, subjective manifest refraction, and corneal topography were analyzed before surgery and 12 months after surgery for both groups. Total HOAs, spherical, coma, and trefoil aberrations were derived from topography data over the 6-mm corneal zone.
In the m-PRK group, the mean preoperative spherical equivalence (SE) changed from -3.15 ± 0.70 D preoperatively to -0.24 ± 0.70 D 1 year postoperatively. Likewise, SE decreased from -3.36 ± 0.63 to -0.25 ± 0.63 D in the t-PRK group 1 year after the surgery. The number of eyes within ± 0.50 D of the target refraction was 89% for m-PRK and 87% for t-PRK groups (p = 0.20). Eighty-four percentage of eyes in the t-PRK group and 80% of eyes in the m-PRK group showed an uncorrected distance visual acuity of 20/25 or better (p = 0.24). Total HOAs, spherical aberration, coma, and trefoil aberrations increased in both groups after surgery, but no statistically significant differences were detected postoperatively among the corneal aberrations.
t-PRK and m-PRK result in comparable refractive results for the correction of low and moderate myopia. Corneal aberrations induced by t-PRK and m-PRK were similar. Epithelial removal techniques do not affect visual, refractive results, or HOAs in PRK.
比较经上皮准分子激光角膜切削术（t-PRK）和机械准分子激光角膜切削术（m-PRK）术后的视力结果和高阶像差（HOAs）。
对接受准分子激光角膜切削术（PRK）的患者的病历进行回顾性评估。45例患者接受m-PRK治疗，45例接受t-PRK治疗。对两组患者在手术前和手术后12个月的视力、主观显验光和角膜地形图进行分析。总高阶像差、球差、彗差和三叶草像差来自6毫米角膜区域的地形图数据。
在m-PRK组中，术前平均球镜等效度（SE）从术前的-3.15±0.70 D变为术后1年的-0.24±0.70 D。同样，t-PRK组术后1年SE从-3.36±0.63降至-0.25±0.63 D。m-PRK组和t-PRK组目标屈光度±0.50 D范围内的眼数分别为89%和87%（p = 0.20）。t-PRK组84%的眼和m-PRK组80%的眼的未矫正远视力为20/25或更好（p = 0.24）。两组术后总高阶像差、球差、彗差和三叶草像差均增加，但术后角膜像差之间未检测到统计学显著差异。
t-PRK和m-PRK在矫正低度和中度近视方面的屈光结果相当。t-PRK和m-PRK引起的角膜像差相似。上皮去除技术不影响PRK的视力、屈光结果或高阶像差。
