Özsu Savaş Sedat, Durmuş Zerrin Gürel, Coşkuner Mustafa Buğra, Bülbül Yılmaz, Öztuna Funda, Özlü Tevfik
Department of Chest Diseases, Karadeniz Technical University School of Medicine, Trabzon, Turkey.
Turk Thorac J. 2017 Jul;18(3):78-81. doi: 10.5152/TurkThoracJ.2017.16050. Epub 2017 Jul 1.
In the last 20 years, with the use of computed tomography (CT) angiography, the number of patients diagnosed with pulmonary thromboembolism (PTE) has increased. At the same time, data show that pulmonary embolism mortality has also reduced in this duration.
In this study, we analyzed records of patients with PTE (using ICD's) in the hospital automation system from 2001 to 2013. Data regarding age, sex, date of diagnosis, diagnosis of cancer, hemodynamic status, initial and maintenance treatment, hospital length of stay, and hospital mortality were recorded. Primary endpoints of the study were hospital length of stay and all-cause hospital mortality.
The total number of patients included in the study was 1185. The median age was 61 years in 2001 and 71 years in 2013. The number of patients who were diagnosed using CT increased from 10% to 92.8%. Between 2001 and 2013, the number of patients diagnosed with PTE increased, and of all patients with PTE, 13.7% was diagnosed in 2009. The hospital length of stay of 13 days declined to 9 days. The use of a vena cava filter in 2007 was 1.1% and that in 2013 was 4.6%. Mortality rate was 15%, however hospital mortality did not significantly differ over the years but varied between 9.4% and 18.8%. Increased use of thrombolytics in patients with massive PTE has been observed over the years. Massive PTE ratio in 2006 was 8.5% and thrombolytic use was 5.8%, however in 2013, these ratios were 2.6%, 6% respectively (p=0.017).
Finally, despite the increased number of patients diagnosed with PTE over the years, the mortality rate was not observed to have changed from 2001 to 2013.
在过去20年中，随着计算机断层扫描（CT）血管造影术的应用，诊断为肺血栓栓塞症（PTE）的患者数量有所增加。与此同时，数据显示在此期间肺栓塞死亡率也有所降低。
在本研究中，我们分析了2001年至2013年医院自动化系统中PTE患者（使用国际疾病分类）的记录。记录了有关年龄、性别、诊断日期、癌症诊断、血流动力学状态、初始和维持治疗、住院时间以及医院死亡率的数据。该研究的主要终点是住院时间和全因医院死亡率。
纳入研究的患者总数为1185例。2001年的中位年龄为61岁，2013年为71岁。使用CT诊断的患者数量从10%增加到92.8%。2001年至2013年期间，诊断为PTE的患者数量增加，在所有PTE患者中，2009年诊断出的占13.7%。住院时间从13天降至9天。2007年腔静脉滤器的使用率为1.1%，2013年为4.6%。死亡率为15%，然而多年来医院死亡率没有显著差异，在9.4%至18.8%之间变化。多年来观察到大量PTE患者中溶栓药物的使用增加。2006年大量PTE的比例为8.5%，溶栓药物的使用率为5.8%，然而在2013年，这些比例分别为2.6%、6%（p = 0.017）。
最后，尽管多年来诊断为PTE的患者数量有所增加，但2001年至2013年期间死亡率并未观察到变化。
