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澳大利亚肺栓塞发病率和死亡率趋势。

Trends in pulmonary embolism morbidity and mortality in Australia.

机构信息

The University of Notre Dame, Sydney, 160 Oxford St, Darlinghurst, NSW 2010 Australia.

出版信息

Thromb Res. 2013 Jul;132(1):19-25. doi: 10.1016/j.thromres.2013.04.032. Epub 2013 May 29.

Abstract

INTRODUCTION

Pulmonary embolism (PE) is a common cause of morbidity and mortality. In this study, we investigated patterns of morbidity and mortality from PE in Australia.

MATERIALS & METHODS: Australian government databases were used to extract data on age and sex specific rates of mortality between 1997 and 2007, and hospital separations between 1998/9 and 2009/10 to examine changes over time and between age and sex groups.

RESULTS

In 2007, 320 deaths were ascribed to PE in Australia, corresponding to a mortality rate of 1.73 per 100,000 population per year. Between 1997 and 2007, the Australian mortality rate decreased in both sexes, but this was significant only in females. By comparison, in 2009/10 there were 9,847 hospital separations for PE, corresponding to a rate of 53.1 per 100,000 population per year. In contrast to the fall in mortality rates, hospital separation rates significantly increased over the study period. Females had higher rates of morbidity and mortality from PE than males. While the mortality rates among the elderly population decreased significantly (from 48.4 to 34.3 per 100,000 population per year in those aged over 85 years), there were significant increases in PE mortality in the younger female age groups.

CONCLUSIONS

Although mortality rates are decreasing, PE remains a significant cause of morbidity and mortality in Australia, especially in females and the elderly. The burden of morbidity and mortality from PE in Australia is comparable to that found in America and a number of European countries.

摘要

介绍

肺栓塞(PE)是发病率和死亡率的常见原因。本研究调查了澳大利亚 PE 的发病率和死亡率模式。

材料与方法

利用澳大利亚政府数据库,提取了 1997 年至 2007 年期间死亡率和 1998/9 年至 2009/10 年期间住院分离的年龄和性别特定发病率数据,以研究随时间的变化以及年龄和性别组之间的变化。

结果

2007 年,澳大利亚有 320 人死于 PE,死亡率为每年每 10 万人 1.73 人。1997 年至 2007 年间,澳大利亚男女的死亡率均有所下降,但女性的下降具有统计学意义。相比之下,2009/10 年有 9847 例 PE 住院分离,发病率为每年每 10 万人 53.1 例。与死亡率下降相反,住院分离率在研究期间显著增加。女性的 PE 发病率和死亡率均高于男性。虽然老年人的死亡率显著下降(85 岁以上人群从每 10 万人每年 48.4 人降至 34.3 人),但年轻女性年龄组的 PE 死亡率却显著上升。

结论

尽管死亡率正在下降,但 PE 仍然是澳大利亚发病率和死亡率的重要原因,尤其是在女性和老年人中。澳大利亚的 PE 发病率和死亡率负担与美国和一些欧洲国家相当。

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