Kshettry Varun R, Nyquist Gurston, Evans James J
Department of Neurological Surgery, Cleveland Clinic, Cleveland, Ohio, United States.
Department of Otolaryngology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States.
J Neurol Surg B Skull Base. 2018 Feb;79(2):S191-S193. doi: 10.1055/s-0037-1620260. Epub 2018 Jan 9.
Surgery for craniopharyngiomas can be challenging due to the involvement of multiple critical neurovascular structures. The expanded endoscopic endonasal approach can provide superior access to suprasellar craniopharyngiomas, particularly with retrochiasmatic extension and significant hypothalamic involvement. We describe the surgical technique used to treat a 30-year-old patient who presented with 4 weeks of worsening vision, fatigue, and memory loss. His vision was counting fingers at 1 feet on the right and 20/800 on the left with a temporal hemianopsia. Laboratory evaluation demonstrated central hypoadrenalism, hypothyroidism, and hypogonadism. Imaging showed a large solid and cystic suprasellar mass. The transtubercular approach with removal of the lateral tubercular strut can provide wide bilateral access to the opticocarotid region. The superior intercavernous sinus must be coagulated and ligated. Initial arachnoid dissection is centered at the midline, mobilizing the superior hypophyseal branches to the optic apparatus laterally. The cyst capsule is opened and care is taken to minimize spillage of cyst fluid into the subarachnoid space. Central debulking and then extracapsular dissection is performed under direct visualization using sharp dissection. Reconstruction of the dura is performed with an inlay/onlay fascia lata button that is held together with four sutures that hold the graft edges against the native dural edges. This is followed by vascularized nasoseptal flap reconstruction. No lumbar drain or nonabsorbable packing is required. The patient's vision had dramatic improvement and by 1 week postoperatively was 20/20 with full visual fields. Postoperative diabetes insipidus was managed with nasal desmopressin. Postoperative MRI demonstrated complete removal. The link to the video can be found at: https://youtu.be/QQxCNUcq1qg .
由于颅咽管瘤涉及多个关键神经血管结构,其手术具有挑战性。扩大经鼻内镜入路能更好地显露鞍上颅咽管瘤,尤其是伴有视交叉后扩展和显著下丘脑受累的情况。我们描述了用于治疗一名30岁患者的手术技术,该患者出现视力恶化、疲劳和记忆力减退4周。他的视力在右侧1英尺处能数指,左侧为20/800,伴有颞侧偏盲。实验室检查显示中枢性肾上腺皮质功能减退、甲状腺功能减退和性腺功能减退。影像学检查显示鞍上有一个巨大的实性和囊性肿块。经结节入路并切除外侧结节支柱可提供对视神经 - 颈动脉区域的广泛双侧显露。必须对海绵间上窦进行凝固和结扎。最初的蛛网膜分离以中线为中心,将垂体上动脉分支向外侧移至视器。打开囊肿包膜时要小心,尽量减少囊液漏入蛛网膜下腔。在直视下使用锐性分离进行中央减压,然后进行囊外分离。用一块嵌入/覆盖的阔筋膜纽扣进行硬脑膜重建,用四根缝线将其固定在一起,使移植边缘紧贴天然硬脑膜边缘。随后进行带血管蒂鼻中隔瓣重建。无需留置腰大池引流管或使用不可吸收的填塞物。患者的视力有显著改善,术后1周时视力达到20/20,视野完整。术后尿崩症用鼻腔去氨加压素治疗。术后MRI显示肿瘤完全切除。视频链接可在:https://youtu.be/QQxCNUcq1qg 找到。