二氢麦角隐亭治疗亨廷顿舞蹈病的经验

Therapeutic experience with transdihydrolisuride in Huntington's disease.

作者信息

Bassi S, Albizzati M G, Corsini G U, Frattola L, Piolti R, Suchy I, Trabucchi M

出版信息

Neurology. 1986 Jul;36(7):984-6. doi: 10.1212/wnl.36.7.984.

DOI:10.1212/wnl.36.7.984

Abstract

Transdihydrolisuride is an ergot derivative with mixed agonist and antagonist effects on central dopamine receptors. We gave the drug orally (1 mg daily) to 10 patients with Huntington's disease. In seven patients, the chorea improved with no adverse effects during the study.

摘要

反式二氢麦角隐亭是一种对中枢多巴胺受体具有激动和拮抗混合作用的麦角衍生物。我们对10例亨廷顿病患者口服该药（每日1毫克）。在7例患者中，舞蹈症得到改善，且在研究期间无不良反应。