Singhal Lipika, Kaur Parvinder, Gautam Vikas
Department of Microbiology, Government Medical College and Hospital, Chandigarh, India.
Department of Biotechnology, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College, Bela, Ropar, Punjab, India.
Indian J Med Microbiol. 2017 Oct-Dec;35(4):469-479. doi: 10.4103/ijmm.IJMM_16_430.
Stenotrophomonas maltophilia, once regarded as an organism of low virulence, has evolved as a significant opportunistic pathogen causing severe human infections in both hospital and community settings, especially amongst highly debilitated patients. Globally, S. maltophilia ranks third amongst the four most common pathogenic non-fermenting Gram-negative bacilli (NFGNBs), others being Pseudomonas aeruginosa, Acinetobacter baumannii and Burkholderia cepacia complex (Bcc). The worth of accurate identification of S. maltophilia comes to the forefront as it needs to be differentiated from other NFGNBs such as Acinetobacter, P. aeruginosa and Bcc due to its inherently contrasting antibiotic susceptibility pattern. Consequently, its correct identification is essential as no single drug is amply effective against all NFGNBs, which hinders initiation of appropriate empirical treatment resulting in increased morbidity and mortality.
嗜麦芽窄食单胞菌曾被视为毒力较低的微生物，现已演变成一种重要的机会致病菌，在医院和社区环境中均会引发严重的人类感染，尤其是在极度虚弱的患者中。在全球范围内，嗜麦芽窄食单胞菌在四种最常见的致病性非发酵革兰氏阴性杆菌（NFGNBs）中排名第三，其他三种分别是铜绿假单胞菌、鲍曼不动杆菌和洋葱伯克霍尔德菌复合体（Bcc）。准确鉴定嗜麦芽窄食单胞菌的重要性凸显出来，因为由于其固有的抗生素敏感性模式与其他NFGNBs（如不动杆菌、铜绿假单胞菌和Bcc）不同，需要将其区分开来。因此，其正确鉴定至关重要，因为没有一种药物能对所有NFGNBs都有充分疗效，这会阻碍开始适当的经验性治疗，从而导致发病率和死亡率增加。
